Colon targeted delivery system
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United States of America Patent
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Mar 21, 2000
Grant Date -
N/A
app pub date -
Sep 20, 1996
filing date -
Oct 17, 1995
priority date (Note) -
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status (Latency Note)
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Abstract
A novel delivery system for targeting drugs to the colon is herein described. The system is a tablet comprised of three parts: 1) an outer enteric coating, 2) an inner semi-permeable polymer membrane containing a plasticizer and 3) a central core comprising swelling excipients and an active ingredient. The novel dosage form described herein will release the drug consistently in the colon by a time-dependent explosion mechanism. This delivery system is particularly suitable for delivering viral protease inhibitors to the colon.
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