Enhancement of antimicrobial peptide activity by metal ions

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United States of America Patent

PATENT NO 6042848
SERIAL NO

08911794

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Abstract

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Provided are methods for maintaining or enhancing the antimicrobial activity of antimicrobial peptides, lytic peptides, and peptide-derived antibiotics by the use of metal ions. Also provided are pharmaceutical and other compositions comprising such peptides and/or at least one metal ion. Also provided are therapeutic and other methods for controlling the growth of undesirable or pathogenic microorganisms in various loci or milieu in, on, or outside the body employing these peptides and metal ions. Also provided are kits comprising containers containing a peptide and a metal ion(s), respectively.

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Patent Owner(s)

Patent OwnerAddress
SIU SCHOOL OF MEDICINEP O BOX 19230 SPRINGFIELD IL 62797

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lawyer, Carl H Springfield, IL 9 183
Watabe, Kounosuke Springfield, IL 3 108

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