Unit dosage forms for treatment of vasoconstriction and related conditions
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United States of America Patent
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Mar 28, 2000
Issued Date -
N/A
app pub date -
Jul 7, 1998
filing date -
Apr 10, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Magnesium is formulated in combination with vitamin E, vitamin C, folate, selenium, and optionally melatonin a unit dosage form for oral administration, for the treatment of vasoconstriction and the physiological and pathological conditions giving rise to vasoconstriction. These active agents complement each other in suppressing these conditions, using a variety of mechanisms operating in conjunction with one another. The inclusion of magnesium in a plurality of forms provides additional advantages in terms of controlling and sustaining the release of magnesium in locations along the digestive tract where the magnesium will have its greatest effectiveness as a therapeutic agent, thus improving control over the clinical bioavailability of magnesium and in improving the selection of appropriate therapeutic ranges.
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