2'-O-Dimethylaminoethyloxyethyl-modified oligonucleotides
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Mar 28, 2000
Grant Date -
N/A
app pub date -
Aug 7, 1998
filing date -
Aug 7, 1998
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
2'-O-Modified ribosyl nucleosides and modified oligonucleotides containing such nucleotides are disclosed. Oligonucleotides are disclosed that have increased binding affinity as shown by molecular modeling experiments. The 2'-O-modified nucleosides of the invention include ring structures that position the sugar moiety of the nucleosides preferentially in 3' endo geometries.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully