Prophylactic and therapeutic agent for hepatic diseases

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United States of America Patent

PATENT NO 6048882
SERIAL NO

08875759

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Abstract

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Hepatic diseases can be prevented or treated by administering an isoprenylamine derivative represented by the general formula (II) ##STR1## [wherein n represents an integer of 4-12, m represents an integer of 0-3, Ar represents a phenyl group, a furyl group, a thienyl group or a pyridyl group, said group being optionally substituted with one or more of an alkyl group of 1-4 carbon atoms, and alkoxy group of 1-4 carbon atoms, a methylenedioxy group, a hydroxy group or a halogen atom, and R represents a hydrogen atom or an alkyl group of 1-4 carbon atoms] or a pharmacologically acceptable salt thereof at a daily dose of 0.01-500 .mu.g/kg. A lipid emulsion of the compound (II) is particularly useful and can be administered at a remarkably lowered dose as compared with other pharmaceutical preparations.

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Patent Owner(s)

Patent OwnerAddress
NISSHIN SEIFUN GROUP INC25 KANDA-NISHIKI-CHO 1-CHOME CHIYODA-KU TOKYO 101-8441

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Inoue, Hitoshi Iruma-gun, JP 129 1831
Kawase, Shigeo Iruma-gun, JP 7 24
Ohwaki, Tatsuya Iruma-gun, JP 4 12
Tahara, Yoshiyuki Ueda, JP 34 165
Yamada, Masako Iruma-gun, JP 29 208
Yamazaki, Hiroyuki Iruma-gun, JP 183 1751

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