Antibodies against human CD40
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United States of America Patent
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Apr 18, 2000
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N/A
app pub date -
Feb 19, 1998
filing date -
Feb 19, 1998
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Abstract
The Applicants have discovered a novel antibody, more specifically a chimerized anti-human CD40 monoclonal antibody, which blocks the interaction between gp39 and CD40. The anti-CD40 antibodies of the present invention are effective in modulating humoral immune responses against T cell-dependent antigens, collagen induced arthritis, and skin transplantation, and are also useful for their anti-inflammatory properties.
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