Cancer susceptibility mutations of BRCA2
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United States of America Patent
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Apr 18, 2000
Grant Date -
N/A
app pub date -
Dec 2, 1997
filing date -
Sep 23, 1997
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Abstract
New mutations have been found in the BRCA2 gene. The mutations are located at nucleotide numbers 2192, 3772, 5193, 5374, 6495 or 6909 of the published nucleotide sequence of BRCA2 gene. A process for identifying a sequence variation in a BRCA2 polynucleotide sequence is disclosed. The identification process includes allele specific sequence-based assays of known sequence variations. The methods can be used for efficient, and accurate detection of a mutation in a test BRCA2 gene sample.
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