Method and compound for detecting low levels of microorganisms
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United States of America Patent
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Apr 18, 2000
Grant Date -
N/A
app pub date -
Dec 4, 1998
filing date -
Aug 25, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method and compound for detecting low levels of microorganisms in biological samples is disclosed. In the method, an antibiotic is conjugated to a detectable label. This antibiotic/label conjugate is then introduced into a sample containing biological material. The antibiotic binds to target microorganism where the label allows for detection of localized concentrations of the antibiotic. A compound to accomplish this method is also described. This compound is an antibiotic conjugated to a fluorescent dye. This dye has an excitation and emission wavelength that are not interfered by substances typically found in biological samples.
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