Organometallic ligands for the localization and quantification of amyloid in vivo and in vitro
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United States of America Patent
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Apr 25, 2000
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N/A
app pub date -
May 7, 1997
filing date -
May 8, 1996
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Abstract
Novel organometallic compounds for binding amyloid are described. Methods using such compounds for determining by imaging the localization or quantification of amyloid fibrils in a mammal, for diagnosing the degree of progression of Alzheimer's disease in a mammal, for monitoring the response to a therapy in a mammal having Alzheimer's disease, for identifying an agent useful for treating Alzheimer's disease, for treating Alzheimer's disease, and for detecting the presence of the infectious form of the prion protein, are also described.
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