Contrast agents comprising two types of gas-containing microparticles
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United States of America Patent
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Apr 25, 2000
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N/A
app pub date -
May 14, 1998
filing date -
Jan 22, 1997
priority date (Note) -
Expired
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Abstract
Ultrasound contrast agents comprising two or more types of gas-containing microparticles which differ in their susceptibility to ultrasonic pressure. Microparticle types having relatively low susceptibility to ultrasonic pressure provide a response to high acoustic energy in the near field where microparticle types with relatively high susceptibility tend to be inactivated through destruction. More highly susceptible microparticle types are effective in the lower acoustic energy environment of the far field, where lower susceptibility microparticle types will tend to exhibit little interaction.
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