US Patent No: 6,060,036

Number of patents in Portfolio can not be more than 2000

Radioactive seed implants

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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Past techniques utilized wet chemistry to produce a carrier free radioisotope for a seed implant. However, by using the technique of ion implantation, it is possible to physically separate the precursor isotope by magnetic means and further, to physically direct a beam of these isotopically pure atoms and to embed them into a suitable carrier body. Thus, formation of the seed implant may be accomplished using dry techniques, that is, no liquid chemistry. The systems and methods disclosed herein are designed to produce a beam of a single stable isotope using an ion implanter and to further implant this single stable isotope below the surface of a carrier body. After neutron activation, these single stable isotopes will produce the isotopes iodine-125, palladium-103, cesium-131, or ytterbium embedded within the carrier body. Optionally, the carrier body may be encapsulated prior to activating the precursor isotope embedded in the carrier body.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
INTERNATIONAL BRACHYTHERAPY, S.A.SENEFFE9

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Armini, Anthony J Manchester, MA 23 613

Cited Art Landscape

Patent Info (Count) # Cites Year
 
CORDIS CORPORATION (3)
4,891,165 Device and method for encapsulating radioactive materials 106 1988
4,946,435 Flexible sealed radioactive film for radiotherapy, and method of making same 56 1988
5,163,896 Pellet for a radioactive seed 103 1991
 
THERAGENICS CORPORATION (3)
4,702,228 X-ray-emitting interstitial implants 140 1985
4,784,116 Capsule for interstitial implants 108 1987
5,405,309 X-ray emitting interstitial implants 132 1993
 
BRUCE S. HOROWITZ, 494 N.W. 165TH STREET, APT. #C302, MIAMI, FLORIDA 33167 (2)
4,697,575 Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member 122 1984
4,815,449 Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member 184 1987
 
Mallinckrodt Medical, Inc. (2)
4,660,547 Method and apparatus for the diagnosis of respiratory diseases and allergies 15 1986
4,803,977 Method and apparatus for the diagnosis of respiratory diseases and allergies 16 1987
 
BEST VASCULAR, INC. (1)
5,683,345 Method and apparatus for treating a desired area in the vascular system of a patient 154 1994
 
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, A PUBLIC ESTABLISHMENT OF FRANCE (1)
4,714,074 Method for protecting human or animal organs against radiation 37 1985
 
ERIC VAN'T HOOFT (1)
4,969,863 Adaptor for remote after-loading apparatus for radiotherapy 74 1988
 
HOOFT, ERIC VAN'T (1)
4,861,520 Capsule for radioactive source 104 1988
 
IBT TECHNOLOGY PARTNERS (1)
5,713,828 Hollow-tube brachytherapy device 161 1995
 
INTERVENTIONAL THERAPIES, LLC (1)
5,503,614 Flexible source wire for radiation treatment of diseases 112 1994
 
MEDI-PHYSICS INC. (1)
4,323,055 Radioactive iodine seed 104 1980
 
NUCLETRON B.V. (1)
4,881,938 Method and an apparatus for treating a part of the body with radioactive material 16 1987
 
ONTARIO CANCER INSTITUTE (1)
4,733,653 Radiotherapy apparatus 25 1985
 
PFC THERAPEUTICS, LLC (1)
4,815,446 Process for treating metastasis of cancerous tumors 33 1985
 
QSA UK LTD (1)
4,827,493 Radiographic source 8 1987
 
The United States of America as represented by the Secretary of the Army (1)
4,398,089 Penetration sensing system with radiation-emitting material 5 1972
 
VAN 'T HOOFT, ERIC (1)
5,030,194 Method and apparatus for effecting radioactive therapy in an animal body 74 1989
 
VAN 'T HOOFT, ERIC, GEZICHTSLAAN 16, 3956 BB LEERSUM, THE NETHERLANDS (1)
4,881,937 Method of treating a part of the body with radioactive material and a trolley for use therein 60 1987
 
Yale-New Haven Hospital, Inc. (1)
4,510,924 Brachytherapy devices and methods employing americium-241 37 1983
 
Other [Check patent profile for assignment information] (5)
4,584,991 Medical device for applying therapeutic radiation 79 1983
4,586,490 Needle inserting instrument means for interstitial radiotherapy 58 1984
4,715,359 Safety bottle and cap for the administration of liquid radioactive iodine 18 1986
5,030,195 Radioactive seed patch for prophylactic therapy 36 1989
5,342,283 Endocurietherapy 220 1990

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
ISORAY MEDICAL, INC. (6)
7,410,458 Brachytherapy implant seeds 1 2003
7,479,261 Method of separating and purifying Cesium-131 from Barium nitrate 2 2005
7,517,508 Method of separating and purifying Yttrium-90 from Strontium-90 0 2005
7,531,150 Method of separating and purifying cesium-131 from barium carbonate 1 2005
7,316,644 Method for preparing particles of radioactive powder containing Cesium-131 for use in brachytherapy sources 2 2005
7,510,691 Method for improving the recovery of cesium-131 from barium carbonate 0 2007
 
SECRETARY OF STATE OF DEFENCE, THE DEFENCE EVALUATION & RESEARCH AGENCY (5)
8,318,194 Implants for administering substances and methods of producing mesoporous implants 0 2010
8,303,975 Implants for administering substances and methods of producing implants 0 2010
8,361,491 Mesoporous implants for administering substances and methods of producing implants 0 2011
8,313,761 Mesoporous implants for administering substances and methods of producing implants 1 2011
8,147,864 Implants for administering substances and methods of producing implants 3 2011
 
UNIVERSITY OF SOUTH FLORIDA (3)
6,496,717 Radio guided seed localization of imaged lesions 10 1999
8,114,006 Radio guided seed localization of imaged lesions 0 2006
7,881,775 Radio guided seed localization of imaged lesions 0 2009
 
BREAST MICROSEED, INC. (2)
6,723,052 Echogenic medical device 38 2001
8,560,052 Echogenic medical device 0 2004
 
PSIMEDICA LIMITED (2)
7,763,277 Implants for administering substances and methods of producing implants 7 1999
8,623,399 Methods of producing mesoporous drug delivery implants 0 2012
 
IMPLANT SCIENCES CORPORATION (1)
6,527,693 Methods and implants for providing radiation to a patient 41 2001
 
STM ACQUISITION SUB. INC. (1)
6,969,344 End portion of first implantation seed spacer that receives and holds any one of implantation seed and second implantation seed spacer 22 2003
 
VARIAN MEDICAL SYSTEMS, INC. (1)
6,676,595 Radioactive medical implant and method of manufacturing 10 1999
 
Other [Check patent profile for assignment information] (2)
7,063,658 System having a carrier substrate and a Ti/P or A1/P coating 0 2001
8,834,837 Method and device for radiotherapy 0 2009