Radioactive seed implants

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6060036
SERIAL NO

09047728

1 Status Updates

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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Past techniques utilized wet chemistry to produce a carrier free radioisotope for a seed implant. However, by using the technique of ion implantation, it is possible to physically separate the precursor isotope by magnetic means and further, to physically direct a beam of these isotopically pure atoms and to embed them into a suitable carrier body. Thus, formation of the seed implant may be accomplished using dry techniques, that is, no liquid chemistry. The systems and methods disclosed herein are designed to produce a beam of a single stable isotope using an ion implanter and to further implant this single stable isotope below the surface of a carrier body. After neutron activation, these single stable isotopes will produce the isotopes iodine-125, palladium-103, cesium-131, or ytterbium embedded within the carrier body. Optionally, the carrier body may be encapsulated prior to activating the precursor isotope embedded in the carrier body.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
INTERNATIONAL BRACHYTHERAPY S.A.SENEFFE4

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Armini, Anthony J Wakefield, MA 22 678

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (6)
* 4323055 Radioactive iodine seed 109 1980
* 4584991 Medical device for applying therapeutic radiation 79 1983
* 4586490 Needle inserting instrument means for interstitial radiotherapy 58 1984
* 4715359 Safety bottle and cap for the administration of liquid radioactive iodine 19 1986
* 5030195 Radioactive seed patch for prophylactic therapy 47 1989
* 5342283 Endocurietherapy 236 1990
 
IBT TECHNOLOGY PARTNERS (1)
* 5713828 Hollow-tube brachytherapy device 168 1995
 
BRUCE S. HOROWITZ, 494 N.W. 165TH STREET, APT. #C302, MIAMI, FLORIDA 33167 (2)
* 4697575 Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member 122 1984
* 4815449 Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member 185 1987
 
CORDIS CORPORATION (3)
* 4891165 Device and method for encapsulating radioactive materials 108 1988
* 4946435 Flexible sealed radioactive film for radiotherapy, and method of making same 66 1988
* 5163896 Pellet for a radioactive seed 116 1991
 
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (1)
* 4714074 Method for protecting human or animal organs against radiation 42 1985
 
THERAGENICS CORPORATION (3)
* 4702228 X-ray-emitting interstitial implants 142 1985
* 4784116 Capsule for interstitial implants 110 1987
* 5405309 X-ray emitting interstitial implants 136 1993
 
Ontario Cancer Institute (1)
* 4733653 Radiotherapy apparatus 27 1985
 
BEST VASCULAR, INC. (1)
* 5683345 Method and apparatus for treating a desired area in the vascular system of a patient 159 1994
 
Yale-New Haven Hospital, Inc. (1)
* 4510924 Brachytherapy devices and methods employing americium-241 39 1983
 
PFC THERAPEUTICS, LLC (1)
* 4815446 Process for treating metastasis of cancerous tumors 34 1985
 
INTERVENTIONAL THERAPIES, LLC (1)
* 5503614 Flexible source wire for radiation treatment of diseases 112 1994
 
QSA UK LTD (1)
* 4827493 Radiographic source 8 1987
 
NUCLETRON B.V. (1)
* 4881938 Method and an apparatus for treating a part of the body with radioactive material 18 1987
 
ERIC VAN'T HOOFT (1)
* 4969863 Adaptor for remote after-loading apparatus for radiotherapy 77 1988
 
MALLINCKRODT MEDICAL, INC. (2)
* 4660547 Method and apparatus for the diagnosis of respiratory diseases and allergies 15 1986
* 4803977 Method and apparatus for the diagnosis of respiratory diseases and allergies 22 1987
 
VAN 'T HOOFT, ERIC (1)
* 5030194 Method and apparatus for effecting radioactive therapy in an animal body 74 1989
 
VAN 'T HOOFT, ERIC, GEZICHTSLAAN 16, 3956 BB LEERSUM, THE NETHERLANDS (1)
* 4881937 Method of treating a part of the body with radioactive material and a trolley for use therein 62 1987
 
HOOFT, ERIC VAN'T (1)
* 4861520 Capsule for radioactive source 109 1988
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
STM ACQUISITION SUB. INC. (1)
6969344 End portion of first implantation seed spacer that receives and holds any one of implantation seed and second implantation seed spacer 24 2003
 
BREAST MICROSEED, INC. (3)
6723052 Echogenic medical device 52 2001
8560052 Echogenic medical device 0 2004
* 2005/0049,490 Echogenic medical device 19 2004
 
Other [Check patent profile for assignment information] (9)
* 7063658 System having a carrier substrate and a Ti/P or A1/P coating 0 2001
* 2003/0092,985 Radio guided seed localization of imaged lesions 5 2002
* 2004/0064,011 Seed for brachytherapy in different medical applications 1 2003
8894969 Method and device for radiotherapy 0 2004
* 2007/0041,900 Method and device for radiotherapy 1 2004
* 2006/0184,018 Radio guided seed localization of imaged lesions 2 2006
* 2007/0038,014 Radio guided seed localization of imaged lesions 5 2006
* 2009/0149,747 RADIO GUIDED SEED LOCALIZATION OF IMAGED LESIONS 0 2009
8834837 Method and device for radiotherapy 0 2009
 
pSiMedica Limited, Inc. (1)
9205051 Methods of producing porous resorbable implants 2 2013
 
RAMOT AT TEL AVIV UNIVERSITY LTD. (2)
* 2010/0062,143 METHOD AND DEVICE FOR RADIOTHERAPY 2 2009
* 2009/0311,413 METHOD AND DEVICE FOR RADIOTHERAPY 0 2009
 
VARIAN MEDICAL SYSTEMS, INC. (1)
* 6676595 Radioactive medical implant and method of manufacturing 11 1999
 
IMPLANT SCIENCES CORPORATION (1)
6527693 Methods and implants for providing radiation to a patient 48 2001
 
IsoRay Medical, Inc. (12)
7410458 Brachytherapy implant seeds 1 2003
* 2005/0101,826 Methods of fabricating brachytherapy implant seeds, methods of fabricating brachytherapy implant seed cores, and brachytherapy implant seeds 2 2003
7479261 Method of separating and purifying Cesium-131 from Barium nitrate 2 2005
* 2006/0051,269 Method of separating and purifying cesium-131 from barium nitrate 4 2005
7517508 Method of separating and purifying Yttrium-90 from Strontium-90 2 2005
* 2006/0018,813 Method of separating and purifying Yttrium-90 from Strontium-90 17 2005
7531150 Method of separating and purifying cesium-131 from barium carbonate 1 2005
* 2006/0024,223 Method of separating and purifying cesium-131 from barium carbonate 4 2005
7316644 Method for preparing particles of radioactive powder containing Cesium-131 for use in brachytherapy sources 2 2005
* 2006/0167,332 Method for preparing particles of radioactive powder containing cesium-131 for use in brachytherapy sources 1 2005
7510691 Method for improving the recovery of cesium-131 from barium carbonate 0 2007
* 2007/0212,285 Method for improving the recovery of cesium-131 from barium carbonate 2 2007
 
UNIVERSITY OF SOUTH FLORIDA (3)
6496717 Radio guided seed localization of imaged lesions 18 1999
8114006 Radio guided seed localization of imaged lesions 0 2006
7881775 Radio guided seed localization of imaged lesions 0 2009
 
BIOCOMPATIBLES UK LIMITED (1)
* 2008/0038,190 Composition apparatus and method for use in imaging 5 2006
 
THE UNIVERSITY OF ALBERT, THE UNIVERSITY OF BRITISH COLUMBIA, CARLETON UNIVERSITY, SINON FRASER UNIVERSITY AND THE UNIVERSITY OF VICTORIA, COLLECTIVELY D/B/A/ TRIUMF (1)
* 2005/0118,098 Radioactive ion 29 2005
 
PSIMEDICA LIMITED (3)
7763277 Implants for administering substances and methods of producing implants 20 1999
8623399 Methods of producing mesoporous drug delivery implants 3 2012
9566235 Implants for administering substances and methods of producing implants 0 2015
 
SECRETARY OF STATE OF DEFENCE, THE DEFENCE EVALUATION & RESEARCH AGENCY (8)
8318194 Implants for administering substances and methods of producing mesoporous implants 3 2010
8303975 Implants for administering substances and methods of producing implants 3 2010
* 2011/0052,657 Implants for administering substances and methods of producing implants 6 2010
8361491 Mesoporous implants for administering substances and methods of producing implants 3 2011
8313761 Mesoporous implants for administering substances and methods of producing implants 8 2011
8147864 Implants for administering substances and methods of producing implants 10 2011
* 2011/0217,353 IMPLANTS FOR ADMINISTERING SUBSTANCES AND METHODS OF PRODUCING IMPLANTS 6 2011
* 2011/0182,967 IMPLANTS FOR ADMINISTERING SUBSTANCES AND METHODS OF PRODUCING IMPLANTS 5 2011
 
PSIVIDA US, INC. (4)
9023896 Porous silicon drug-eluting particles 2 2010
* 2010/0278,931 POROUS SILICON DRUG-ELUTING PARTICLES 5 2010
9333173 Bioerodible silicon-based devices for delivery of therapeutic agents 0 2011
9486459 Porous silicon drug-eluting particles 0 2015
* Cited By Examiner