Polyketide derivatives and recombinant methods for making same

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United States of America Patent

PATENT NO 6060234
SERIAL NO

08858003

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Abstract

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The invention provides novel erythromycin derivatives in which methyl groups on the macrolactone ring have been substituted with --H, --Et, and/or --OH. The invention also provides reagents such as isolated polynucleotides, vectors comprising the polynucleotides and host cells transformed with the vectors for making the novel compounds. Methods for making the compounds utilizing genetic engineering techniques are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
ABBOTT LABORATORIES100 ABBOTT PARK ROAD ABBOTT PARK IL 60064-3500

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kakavas, Stephan J Buffalo Grove, IL 5 80
Katz, Leonard Wheeling, IL 51 599
Pereda-Lopez, Ana Mundelein, IL 5 136
Ruan, Xiaoan Lake Bluff, IL 4 78
Stassi, Diane L Highland Park, IL 7 111
Summers, Jr Richard G Nashotah, WI 4 107

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