Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
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United States of America Patent
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May 9, 2000
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N/A
app pub date -
Jul 11, 1996
filing date -
Jul 11, 1996
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Abstract
Shaped medical devices, e.g. stents, having improved mechanical properties and structural integrity are disclosed. The devices comprise shaped polymeric hydrogels which are both ionically and non-ionically crosslinked and which exhibit improved structural integrity after selective removal of the crosslinking ions. Process for making such devices are also disclosed wherein an ionically crosslinkable polymer is both ionically and non-ionically crosslinked to form a shaped medical device. When implanted in the body, selective in-vivo stripping of the crosslinking ions produces a softer, more flexible implant having improved structural integrity.
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