US Patent No: 6,060,582

Number of patents in Portfolio can not be more than 2000

Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

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Abstract

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMAUSTIN, TX2784

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Desai, Neil P Santa Monica, CA 160 4342
Hill-West, Jennifer L Austin, TX 13 765
Hubbell, Jeffrey A Zurich, CH 120 3670
Pathak, Chandrashekhar P Austin, TX 73 2558
Sawhney, Amarpreet S Lexington, MA 109 3736

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Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
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