Pharmaceutical compositions of bactericidal/permeability increasing protein (BPI)

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United States of America Patent

PATENT NO 6066620
SERIAL NO

09313525

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Abstract

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Polypeptide pharmaceutical compositions having improved stability and resistance to aggregation, particle formation and precipitation comprising a polypeptide pharmaceutical and poloxamer surfactants alone, or in combination with polysorbate surfactants. Preferred polypeptides stabilized are bactericidal/permeability increasing (BPI) protein, biologically active fragments of BPI, biologically active analogs of BPI, and biologically active variants of BPI.

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Patent Owner(s)

Patent OwnerAddress
XOMA CORPORATIONBERKELEY CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, C Paul Chatsworth, CA 5 87
McGregor, Weldon Courtney Los Angeles, CA 4 48
Stubstad, James Lafayette, CA 5 87

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