Bioerodible polymeric semi-interpenetrating network alloys for surgical plates and bone cements, and method for making same
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United States of America Patent
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Jun 6, 2000
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N/A
app pub date -
Apr 18, 1997
filing date -
Apr 18, 1997
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Abstract
A bioerodible polymeric semi-IPN alloy which comprises a first bioerodible polymer capable of producing acidic products upon hydrolytic degradation; a second bioerodible polymer, which provides a biopolymeric scaffolding or internal reinforcement; and optionally a buffering compound that buffers the acidic products within a desired pH range. In a preferred embodiment, the second bioerodible polymer comprises polypropylene fumarate (PPF), which is cross-linked, desirably by a vinyl monomer such as vinyl pyrrolidone (VP) to form the biopolymeric scaffolding which provides the semi-IPN with dimensional and geometric stability.
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