Cellular apoptosis susceptibility protein (CSP)

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United States of America Patent

PATENT NO 6072031
SERIAL NO

08918190

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Abstract

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The cDNA and amino acid sequences for a cellular apoptosis susceptibility (CAS) protein are used to detect expression and amplification of the CAS gene in normal and cancer cells. An antisense CAS gene sequence introduced into living cells inhibits CAS protein activity and thus prevents or inhibits apoptosis in the cells.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICESWASHINGTON DC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brinkmann, Ulrich Kensington, MD 116 1819
Pastan, Ira Potomac, MD 66 1404

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