Small molecular weight ligand-hexose containing clearing agents
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United States of America Patent
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Jun 13, 2000
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N/A
app pub date -
Dec 7, 1994
filing date -
Jun 9, 1992
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Abstract
Small molecule weight clearing agents containing ligands such as biotin or biotin analogs and hexose residue, in particular galactose or N-acetyl galactosamine residues are taught. These clearing agents effectively clear anti-ligand containing conjugates in vivo via hepatocyte receptor mediated clearance mechanisms.
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