Methylene blue and toluidene blue mediated fluorescence diagnosis of cancer
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United States of America Patent
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Jul 4, 2000
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app pub date -
Aug 25, 1998
filing date -
Aug 25, 1997
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Abstract
A method for differentiating between normal tissue and tumor tissue within a tissue field. The method includes the application of a photosensitizer solution to the tissue field and the subsequent illumination and measurement of fluorescent intensity across the tissue field. The measurement of relative fluorescent intensity across the tissue field provides information relating to the existence or nonexistence of tumor tissue. Solution concentrations of methylene blue and or toluidene blue are utilized to provide the greatest differentiability between normal tissue and tumor tissue within the tissue field.
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