Transformed industrial bacillus strains and methods for making and using them
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Jul 4, 2000
Issued Date -
N/A
app pub date -
Nov 5, 1997
filing date -
Jul 6, 1983
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Expired
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Abstract
Novel methods and novel industrial unicellular microorganism strains, particularly industrial Bacillus strains, are provided for enhanced production of endogenous and exogenous polypeptides. Cloning vehicles containing the gene expressing the polypeptide of interest are introduced into a compatible host. Transformed hosts harboring the introduced vehicle in a stable way by integration of the vehicle into the host cells chromosome are selected. Efficient transfer of the vehicle containing the gene of interest is achieved, with the resulting industrial strain transformants being effective, stable producers of the desired polypeptide product.
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