Sulfonamide substituted aspartic acid interleukin-1.beta. converting enzyme inhibitors

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United States of America Patent

PATENT NO 6083981
SERIAL NO

09284425

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compounds that are inhibitors of interleukin-1.beta. converting enzyme that have the Formula I, II, or III. ##STR1## This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock reperfusion injury, Alzheimer's disease, and shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1.beta. converting enzyme.

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Patent Owner(s)

Patent OwnerAddress
ABBOTT GMBH & CO KGWIESBADEN WIESBADEN HESSIAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allen, Hamish John Boylston, MA 7 70
Brady, Kenneth Dale Worcester, MA 7 77
Harter, William Glen Chelsea, MI 9 82
Lunney, Elizabeth Ann Ann Arbor, MI 12 55
Plummer, Mark Stephen Dexter, MI 15 169
Sawyer, Tomi Southborough, MA 9 41
Shahripour, Aurash Ann Arbor, MI 14 76
Walker, Nigel Dossenheim, DE 12 178

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