Process for preparing N-demethyl-N-alkyl erythromycin derivatives

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United States of America Patent

PATENT NO 6084079
SERIAL NO

09080340

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Abstract

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The claimed invention relates to a novel process of preparing N-demethyl-N-alkyl-4'-deoxy erythromycin A and B. The process comprises protecting the 2'-hydroxy or the 2'- and 11-hydroxy of a N-demethyl-4'-deoxy erythromycin derivative having the formula: ##STR1## where R.sub.b is H or OH, with a silyl protecting group and alkylating the N-position of the desosamine sugar.

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Patent Owner(s)

Patent OwnerAddress
ABBVIE INC1 NORTH WAUKEGAN ROAD NORTH CHICAGO IL 60064

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kemp, Anne H 1365 Michele Dr., Palatine, IL 60067 3 52
Keyes, Robert F 3621 109.sup.th St., Kenosha, WI 53142 9 108
Patel, Hemant H 1552 Acorn Ct., Gurnee, IL 60031 7 51
Premchandran, Ramiya H 6658 Foxworth La., Gurnee, IL 60031 7 24
Thomas, Albert V 1525 Eric La., Libertyville, IL 60048 8 53

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