Pharmaceutical non inorganic saline solutions for endonasal administration of a calcitonin
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United States of America Patent
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Jul 11, 2000
Issued Date -
N/A
app pub date -
Aug 8, 1997
filing date -
Feb 8, 1995
priority date (Note) -
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Abstract
The subject-matter of the invention are pharmaceutical non inorganic saline solutions for endonasal administration containing: (a) a calcitonin, preferably salmon or alternatively carbacalcitonin (elcatonin), or its pharmaceutically acceptable salts; characterized in that it further contains the organic excipients; (b) N-(methyl)-glucamine or glucamine; (c) tromethamine; (d) citric acid; and (e) polyvinylpyrrolidone ranging from K15 to K120. These are odorless and tasteless and thus have improved patient's compliance not having the undesirable secondary effects of known compositions as well as permit a complete and accurate analysis of the active principle and develop less degradation products during storage.
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