Method for destroying residual lens epithelial cells
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United States of America Patent
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-
Jul 18, 2000
Issued Date -
N/A
app pub date -
Jan 16, 1997
filing date -
Oct 21, 1994
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A method for destroying residual lens epithelial cells in an eye in order to prevent the occurrence of posterior chamber opacification. A solution containing a basement membrane binding agent conjugated to a cytotoxic agent is introduced into the lens capsule. The solution is maintained in the lens capsule for a period of time sufficient to permit the basement membrane binding agent to bind to basement membranes within the lens capsule. The solution is then removed from the lens capsule, whereby a portion of the basement membrane binding agent remains bonded to basement membranes within the lens capsule, thereby exposing residual lens epithelial cells disposed on the basement membrane to the cytotoxic agent.
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