Pharmaceutical compositions for intranasal spray administration of ketorolac tromethamine

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United States of America Patent

PATENT NO 6090368
SERIAL NO

09033994

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Abstract

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A pharmaceutical composition of a water soluble drug admixed with an aqueous bioadhesive cellulosic polymer containing microcrystalline particles. When sprayed (via a conventional spray device) into the nose, drug molecules are retained in contact with the nasal membrane. The drug composition comprises ketorolac tromethamine in an aqueous nasal polymeric spray formulation that without the addition of any permeation enhancer will promote drug absorption and provides absolute drug bioavailability greater than 90%.

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Patent Owner(s)

Patent OwnerAddress
COUNCIL ON POSTSECONDARY EDUCATION560 JEFFERSON BOULEVARD SUITE 100 WARWICK RI 02886

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Needham, Thomas E Wakefield, RI 4 209
Quadir, Muhammad Kingston, RI 1 23
Zia, Hossein Wakefield, RI 2 25

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