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Abstract

A substance countering agent especially for an abused drug or alcohol or a contraceptive agent is contained in a flexible adherent sheet or patch used to achieve the transdermal delivery of the agent through the skin of a person. The patch is limp, fragile, and non-self-supporting. The patch has a weak structure and is sufficiently limp and fragile so that the patch cannot be removed from the skin and later reapplied to the skin as a smooth planar covering. A compliance verification method is also provided for compulsory drug administration. This novel method includes providing a flexible adhesive patch containing a substance countering agent to be administered transdermally to the patient and maintaining the patch sufficiently limp and fragile so that the patch cannot be removed from the skin and later reapplied to the skin as a smooth planar covering. Prior to being applied to the skin, a supporting sheet or carrier is provided for supporting the patch in an outstretched, wrinkle-free condition. The patch is applied to the skin and the supporting sheet or carrier is removed, leaving the patch on the skin as a thin, membranous covering.

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First Claim