US Patent No: 6,099,454

Number of patents in Portfolio can not be more than 2000

Perfusion balloon and radioactive wire delivery system

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Abstract

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A catheter capable of irradiating blood vessel walls to inhibit restenosis after angioplasty. Catheters are capable of simultaneous irradiation and angioplasty. Preferred catheters include a helical perfusion balloon having closely spaced or contacting adjacent windings when inflated. A helical balloon with strand windings having little space therebetween decreases the amount of blood between the balloon exterior surface and vessel walls. A removable, sheathed, elongate radiation source is used with some embodiments. A fixed, flexible sheath partitioning the catheter lumen into sterile and non-sterile portions is included in another embodiment. Internal rather than external perfusion and use of gas to inflate the balloon decrease the absorption of beta radiation by blood, and liquid inflation fluid, respectively.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BOSTON SCIENTIFIC SCIMED, INC.MAPLE GROVE, MN4840

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hastings, Roger N Maple Grove, MN 159 4779
Urick, Michael J Rogers, MN 35 787

Cited Art Landscape

Patent Info (Count) # Cites Year
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (15)
4,782,834 Dual lumen dilatation catheter and method of manufacturing the same 172 1987
5,084,002 Ultra-thin high dose iridium source for remote afterloader 83 1988
4,976,680 Apparatus for in situ radiotherapy 107 1988
5,103,395 System for remote positioning of a radioactive source into a patient including means for protection against improper patient exposure to radiation 55 1990
5,575,749 Ultra-thin high dose radioactive source wire 66 1990
5,092,834 Apparatus and method for the remote handling of highly radioactive sources in the treatment of cancer 61 1990
5,183,455 Apparatus for in situ radiotherapy 84 1990
5,139,473 Apparatus and method for the remote handling of highly radioactive sources in the treatment of cancer 62 1991
5,267,960 Tissue engaging catheter for a radioactive source wire 151 1992
5,624,372 Source wire for localized internal irradiation of tissue 73 1994
5,851,172 Afterloader with active force feedback 54 1995
5,807,231 Source wire for localized internal irradiation of tissue 57 1995
5,871,436 Radiation therapy method and device 108 1996
5,782,740 Radiation dose delivery catheter with reinforcing mandrel 117 1996
5,851,171 Catheter assembly for centering a radiation source within a body lumen 73 1997
 
BOSTON SCIENTIFIC SCIMED, INC. (7)
5,032,113 Innerless catheter 161 1989
4,976,690 Variable stiffness angioplasty catheter 135 1990
5,882,290 Intravascular radiation delivery system 46 1996
5,871,437 Radioactive stent for treating blood vessels to prevent restenosis 118 1996
5,873,811 Composition containing a radioactive component for treatment of vessel wall 47 1997
5,865,720 Expandable and retrievable radiation delivery system 43 1997
5,855,546 Perfusion balloon and radioactive wire delivery system 65 1997
 
CORDIS CORPORATION (5)
5,163,896 Pellet for a radioactive seed 102 1991
5,540,659 Irradiation catheter and method of use 161 1994
5,891,091 Irradiation catheter and method of use 54 1996
5,879,282 Catheter having an expandable radioactive source 95 1997
5,863,285 Balloon catheter with radioactive means 73 1997
 
INTERVENTIONAL THERAPIES, LLC (5)
4,819,618 Iridium/platinum implant, method of encapsulation, and method of implantation 102 1987
5,141,487 Attachment of radioactive source and guidewire in a branchy therapy source wire 80 1989
5,556,389 Method and apparatus for treating stenosis or other constriction in a bodily conduit 114 1994
5,503,614 Flexible source wire for radiation treatment of diseases 112 1994
5,618,266 Catheter for maneuvering radioactive source wire to site of treatment 146 1994
 
NEOCARDIA, LLC (4)
5,643,171 Method and apparatus for uniform radiation treatment of vascular lumens 168 1994
5,616,114 Intravascular radiotherapy employing a liquid-suspended source 142 1994
5,662,580 Combined angioplasty and intravascular radiotherapy method and apparatus 138 1995
5,882,291 Device and method for controlling dose rate during intravascular radiotherapy 94 1996
 
United States Surgical Corporation (4)
5,857,956 Flexible source wire for localized internal irradiation of tissue 59 1995
5,833,593 Flexible source wire for localized internal irradiation of tissue 95 1995
5,800,333 Afterloader provided with remote control unit 92 1996
5,840,064 Method and apparatus for treating stenosis or other constriction in a bodily conduit 73 1996
 
THERAGENICS CORPORATION (3)
4,702,228 X-ray-emitting interstitial implants 136 1985
4,784,116 Capsule for interstitial implants 105 1987
5,405,309 X-ray emitting interstitial implants 128 1993
 
BRUCE S. HOROWITZ, 494 N.W. 165TH STREET, APT. #C302, MIAMI, FLORIDA 33167 (2)
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4,815,449 Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member 181 1987
 
CYTYC CORPORATION (2)
5,429,582 Tumor treatment 118 1991
5,611,767 Radiation treatment of tumors using inflatable devices 109 1994
 
ISOSTENT, INC. (2)
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5,722,984 Antithrombogenic radioactive coating for an intravascular stent 162 1996
 
MED INSTITUTE, INC. (2)
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5,484,384 Minimally invasive medical device for providing a radiation treatment 203 1994
 
Medical Innovative Technologies R&D Limited Partnership (2)
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5,176,617 Use of a stent with the capability to inhibit malignant growth in a vessel such as a biliary duct 231 1991
 
PROGRESSIVE ANGIOPLASTY SYSTEMS, INC. (2)
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5,411,466 Apparatus for restenosis treatment 228 1994
 
Sauerwein; Kurt (2)
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4,631,415 Radiation treatment apparatus 44 1984
 
Schneider (Europe) A.G. (2)
5,688,220 Medical appliance for treatment by ionizing radiation 64 1995
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Technical Operations, Incorporated (2)
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4,281,252 Coupling apparatus for portable radiography systems 35 1979
 
The Trustees of Columbia University in the City of New York (2)
5,503,613 Apparatus and method to reduce restenosis after arterial intervention 175 1994
5,707,332 Apparatus and method to reduce restenosis after arterial intervention 112 1995
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (1)
5,282,781 Source wire for localized radiation treatment of tumors 158 1990
 
ABBOTT LABORATORIES (1)
5,863,284 Devices and methods for radiation treatment of an internal body organ 153 1996
 
BEST VASCULAR, INC. (1)
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BIOTRACES, INC. (1)
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Campaignie ORIS Industrie (1)
4,851,694 Device for driving and positioning a source holder in an applicator used in radiotherapy 55 1988
 
CARDIOVASCULAR DYNAMICS, INC. (1)
5,782,742 Radiation delivery balloon 112 1997
 
CATHETER ABLATION SOLUTIONS LLC (1)
5,649,924 Medical device for irradiation of tissue 117 1995
 
EMORY UNIVERSITY (1)
5,899,882 Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient 181 1996
 
ERIC VAN'T HOOFT (1)
4,969,863 Adaptor for remote after-loading apparatus for radiotherapy 74 1988
 
FORSCHUNGSZENTRUM KARLSRUHE GMBH (1)
5,674,177 Vascular implant 52 1995
 
GAYLORD CONTAINER CORPORATION (1)
5,795,286 Radioisotope impregnated sheet of biocompatible material for preventing scar tissue formation 46 1996
 
HEARTPORT, INC. (1)
5,370,685 Endovascular aortic valve replacement 439 1991
 
HENRY FORD HOSPOTAL A MI CORP (1)
4,763,642 Intracavitational brachytherapy 129 1986
 
HITACHI, LTD. (1)
5,538,494 Radioactive beam irradiation method and apparatus taking movement of the irradiation area into consideration 144 1995
 
HOOFT, ERIC VAN'T (1)
4,861,520 Capsule for radioactive source 103 1988
 
Industrial Nuclear Company, Inc. (1)
4,314,157 Safety lock for radiography exposure device 33 1979
 
ISOSTENT, LLC (1)
5,605,530 System for safe implantation of radioisotope stents 94 1995
 
ISOTECH, L.L.C. (1)
5,897,573 Radioactive medical suture and method of making the same 31 1997
 
ISOTOPEN-TECHNIK DR. SAUERWEIN GMBH (1)
5,120,973 Method and device for inserting a radioactive radiation source into an applicator and withdrawing it therefrom 48 1991
 
KABE LABORTECHNIK GMBH (1)
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LOCALMED, INC. (1)
5,840,008 Radiation emitting sleeve catheter and methods 83 1995
 
MEDTRONIC AVE, INC. (1)
5,545,132 Helically grooved balloon for dilatation catheter and method of using 156 1993
 
MRKR L.L.C. (1)
5,498,227 Retrievable, shielded radiotherapy implant 144 1993
 
NUCLETRON B.V. (1)
5,084,001 Method and apparatus for effecting radioactive therapy in an animal body 106 1990
 
OLYMPUS OPTICAL CO., LTD. (1)
5,106,360 Thermotherapeutic apparatus 454 1991
 
PYRAMID TECHNOLOGIES INTERNATIONAL, INC. (1)
4,936,823 Transendoscopic implant capsule 179 1988
 
SAHOTA, HARVINDER (1)
5,417,653 Method for minimizing restenosis 95 1993
 
SANDIA CORPORATION (1)
4,976,266 Methods of in vivo radiation measurement 89 1988
 
SIEMENS MEDICAL SYSTEMS, INC. (1)
5,820,553 Identification system and method for radiation therapy 227 1996
 
TARGET THERAPEUTICS, INC. (1)
5,409,015 Deformable tip super elastic guidewire 115 1993
 
The Beth Israel Hospital Association (1)
4,799,479 Method and apparatus for angioplasty 292 1987
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
4,763,671 Method of treating tumors using selective application of heat and radiation 130 1986
 
UNIVERSITY OF VIRGINIA (1)
4,963,128 Chest tube and catheter grid for intrathoracic afterload radiotherapy 42 1989
 
VAN 'T HOOFT, ERIC (1)
5,030,194 Method and apparatus for effecting radioactive therapy in an animal body 74 1989
 
VAN 'T HOOFT, ERIC, GEZICHTSLAAN 16, 3956 BB LEERSUM, THE NETHERLANDS (1)
4,881,937 Method of treating a part of the body with radioactive material and a trolley for use therein 60 1987
 
WALL CARDIOVASCULAR TECHNOLOGIES, LLC (1)
5,843,163 Expandable stent having radioactive treatment means 80 1996
 
WEINSTEIN, JOSEPH S. (1)
5,213,561 Method and devices for preventing restenosis after angioplasty 224 1992
 
WILLIAM BEAUMONT HOSPITAL (1)
5,391,139 Real time radiation treatment planning system 108 1994
 
Other [Check patent profile for assignment information] (15)
4,244,357 Method and apparatus for homogeneously irradiating the vaginal mucosa with a linear source uterovaginal applicator 40 1979
4,364,376 Method and device for injecting a bolus of material into a body 39 1979
4,588,395 Catheter and method 213 1980
4,584,991 Medical device for applying therapeutic radiation 79 1983
4,897,076 Detachable and remote controllable afterloading device for radiation 62 1985
5,199,939 Radioactive catheter 270 1990
5,147,282 Irradiation loading apparatus 85 1990
5,344,383 Apparatus for radioactive treatment inside the human body and the method using the same 30 1992
5,425,720 Medical needle unit 83 1993
5,308,356 Passive perfusion angioplasty catheter 144 1993
5,653,683 Intracavitary catheter for use in therapeutic radiation procedures 110 1995
5,730,698 Balloon expandable temporary radioisotope stent system 195 1995
5,816,259 Method for the diagnosis and treatment of cancer by the accumulation of radioactive precipitates in targeted cells 42 1997
5,720,717 Intracavitary catheter for use in therapeutic radiation procedures 122 1997
5,816,999 Flexible catheter for the delivery of ionizing radiation to the interior of a living body 52 1997

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
SALUTARIS MEDICAL DEVICES, INC. (3)
8,430,804 Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye 1 2009
8,608,632 Methods and devices for minimally-invasive extraocular delivery of radiation and/or pharmaceutics to the posterior portion of the eye 0 2011
8,597,169 Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye 0 2013
 
ZOLL CIRCULATION, INC. (3)
6,610,083 Multiple lumen heat exchange catheters 36 2001
7,566,341 Multiple lumen heat exchange catheters 7 2003
8,409,265 Multiple lumen heat exchange catheters 1 2009
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (2)
6,579,221 Proximal catheter shaft design and catheters incorporating the proximal shaft design 5 2001
7,912,531 Magnetic resonance imaging coils 1 2003
 
BOSTON SCIENTIFIC SCIMED, INC. (2)
6,258,019 Catheter for intraluminal treatment of a vessel segment with ionizing radiation 24 1999
8,669,360 Methods of converting amorphous drug substance into crystalline form 0 2011
 
MEDTRONIC AVE, INC. (2)
6,679,860 Intraluminal therapy catheter with inflatable helical member and methods of use 11 2001
6,746,392 Brachytherapy catheter with twisted lumens and methods of use 19 2001
 
ACROSTAK CORP. (1)
8,734,314 Method and kit for delivery of brachytherapy to a subject 0 2008
 
CIANNA MEDICAL, INC. (1)
8,771,161 Expandable brachytherapy apparatus and methods for using them 0 2009
 
HEMOTEQ AG (1)
8,597,720 Medical product for treating stenosis of body passages and for preventing threatening restenosis 0 2008
 
LOMA VISTA MEDICAL, INC. (1)
8,708,955 Inflatable medical devices 0 2009
 
PROGENIX, LLC (1)
6,312,374 Radioactive wire placement catheter 60 1999
 
SALUTARIS MEDICAL DEVIES, INC. (1)
7,273,445 Intraocular brachytherapy device and method 24 2004

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