US Patent No: 6,099,454
Number of patents in Portfolio can not be more than 2000
Perfusion balloon and radioactive wire delivery system
Stats
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Aug 8, 2000
Issued date -
Mar 6, 1997
filing date -
08/812,248
serial no -
Expired
status
Importance
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Abstract
A catheter capable of irradiating blood vessel walls to inhibit restenosis after angioplasty. Catheters are capable of simultaneous irradiation and angioplasty. Preferred catheters include a helical perfusion balloon having closely spaced or contacting adjacent windings when inflated. A helical balloon with strand windings having little space therebetween decreases the amount of blood between the balloon exterior surface and vessel walls. A removable, sheathed, elongate radiation source is used with some embodiments. A fixed, flexible sheath partitioning the catheter lumen into sterile and non-sterile portions is included in another embodiment. Internal rather than external perfusion and use of gas to inflate the balloon decrease the absorption of beta radiation by blood, and liquid inflation fluid, respectively.
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First Claim
Related Publications
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 4,782,834 Dual lumen dilatation catheter and method of manufacturing the same | 166 | 1987 | |
| 5,084,002 Ultra-thin high dose iridium source for remote afterloader | 83 | 1988 | |
| 4,976,680 Apparatus for in situ radiotherapy | 97 | 1988 | |
| 5,103,395 System for remote positioning of a radioactive source into a patient including means for protection against improper patient exposure to radiation | 55 | 1990 | |
| 5,575,749 Ultra-thin high dose radioactive source wire | 66 | 1990 | |
| 5,092,834 Apparatus and method for the remote handling of highly radioactive sources in the treatment of cancer | 60 | 1990 | |
| 5,183,455 Apparatus for in situ radiotherapy | 83 | 1990 | |
| 5,139,473 Apparatus and method for the remote handling of highly radioactive sources in the treatment of cancer | 59 | 1991 | |
| 5,267,960 Tissue engaging catheter for a radioactive source wire | 142 | 1992 | |
| 5,624,372 Source wire for localized internal irradiation of tissue | 73 | 1994 | |
| 5,851,172 Afterloader with active force feedback | 54 | 1995 | |
| 5,807,231 Source wire for localized internal irradiation of tissue | 55 | 1995 | |
| 5,871,436 Radiation therapy method and device | 102 | 1996 | |
| 5,782,740 Radiation dose delivery catheter with reinforcing mandrel | 109 | 1996 | |
| 5,851,171 Catheter assembly for centering a radiation source within a body lumen | 65 | 1997 | |
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| 5,032,113 Innerless catheter | 155 | 1989 | |
| 4,976,690 Variable stiffness angioplasty catheter | 128 | 1990 | |
| 5,882,290 Intravascular radiation delivery system | 45 | 1996 | |
| 5,871,437 Radioactive stent for treating blood vessels to prevent restenosis | 108 | 1996 | |
| 5,873,811 Composition containing a radioactive component for treatment of vessel wall | 46 | 1997 | |
| 5,865,720 Expandable and retrievable radiation delivery system | 43 | 1997 | |
| 5,855,546 Perfusion balloon and radioactive wire delivery system | 63 | 1997 | |
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| 5,163,896 Pellet for a radioactive seed | 91 | 1991 | |
| 5,540,659 Irradiation catheter and method of use | 150 | 1994 | |
| 5,891,091 Irradiation catheter and method of use | 45 | 1996 | |
| 5,879,282 Catheter having an expandable radioactive source | 89 | 1997 | |
| 5,863,285 Balloon catheter with radioactive means | 68 | 1997 | |
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| 4,819,618 Iridium/platinum implant, method of encapsulation, and method of implantation | 100 | 1987 | |
| 5,141,487 Attachment of radioactive source and guidewire in a branchy therapy source wire | 79 | 1989 | |
| 5,556,389 Method and apparatus for treating stenosis or other constriction in a bodily conduit | 106 | 1994 | |
| 5,503,614 Flexible source wire for radiation treatment of diseases | 111 | 1994 | |
| 5,618,266 Catheter for maneuvering radioactive source wire to site of treatment | 136 | 1994 | |
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| 5,643,171 Method and apparatus for uniform radiation treatment of vascular lumens | 159 | 1994 | |
| 5,616,114 Intravascular radiotherapy employing a liquid-suspended source | 138 | 1994 | |
| 5,662,580 Combined angioplasty and intravascular radiotherapy method and apparatus | 129 | 1995 | |
| 5,882,291 Device and method for controlling dose rate during intravascular radiotherapy | 86 | 1996 | |
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| 5,857,956 Flexible source wire for localized internal irradiation of tissue | 58 | 1995 | |
| 5,833,593 Flexible source wire for localized internal irradiation of tissue | 93 | 1995 | |
| 5,800,333 Afterloader provided with remote control unit | 89 | 1996 | |
| 5,840,064 Method and apparatus for treating stenosis or other constriction in a bodily conduit | 67 | 1996 | |
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| 4,702,228 X-ray-emitting interstitial implants | 133 | 1985 | |
| 4,784,116 Capsule for interstitial implants | 103 | 1987 | |
| 5,405,309 X-ray emitting interstitial implants | 125 | 1993 | |
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| 4,706,652 Temporary radiation therapy | 109 | 1985 | |
| 4,815,449 Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member | 178 | 1987 | |
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| 5,429,582 Tumor treatment | 104 | 1991 | |
| 5,611,767 Radiation treatment of tumors using inflatable devices | 95 | 1994 | |
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| 5,840,009 Radioisotope stent with increased radiation field strength at the ends of the stent | 115 | 1995 | |
| 5,722,984 Antithrombogenic radioactive coating for an intravascular stent | 140 | 1996 | |
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| 5,354,257 Minimally invasive medical device for providing a radiation treatment | 204 | 1991 | |
| 5,484,384 Minimally invasive medical device for providing a radiation treatment | 177 | 1994 | |
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| 5,059,166 Intra-arterial stent with the capability to inhibit intimal hyperplasia | 404 | 1989 | |
| 5,176,617 Use of a stent with the capability to inhibit malignant growth in a vessel such as a biliary duct | 219 | 1991 | |
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| 5,302,168 Method and apparatus for restenosis treatment | 188 | 1991 | |
| 5,411,466 Apparatus for restenosis treatment | 205 | 1994 | |
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| 4,220,864 Radiographic apparatus | 31 | 1978 | |
| 4,631,415 Radiation treatment apparatus | 44 | 1984 | |
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| 5,688,220 Medical appliance for treatment by ionizing radiation | 64 | 1995 | |
| 5,728,042 Medical appliance for ionizing radiation treatment having radiopaque markers | 73 | 1995 | |
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| 4,225,790 Storage reel assembly | 48 | 1978 | |
| 4,281,252 Coupling apparatus for portable radiography systems | 35 | 1979 | |
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| 5,503,613 Apparatus and method to reduce restenosis after arterial intervention | 167 | 1994 | |
| 5,707,332 Apparatus and method to reduce restenosis after arterial intervention | 108 | 1995 | |
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| 5,282,781 Source wire for localized radiation treatment of tumors | 147 | 1990 | |
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| 5,863,284 Devices and methods for radiation treatment of an internal body organ | 128 | 1996 | |
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| 5,683,345 Method and apparatus for treating a desired area in the vascular system of a patient | 146 | 1994 | |
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| 5,532,122 Quantitation of gamma and x-ray emitting isotopes | 41 | 1993 | |
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| 4,851,694 Device for driving and positioning a source holder in an applicator used in radiotherapy | 55 | 1988 | |
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| 5,782,742 Radiation delivery balloon | 101 | 1997 | |
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| 5,649,924 Medical device for irradiation of tissue | 105 | 1995 | |
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| 5,899,882 Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient | 161 | 1996 | |
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| 4,969,863 Adaptor for remote after-loading apparatus for radiotherapy | 74 | 1988 | |
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| 5,795,286 Radioisotope impregnated sheet of biocompatible material for preventing scar tissue formation | 45 | 1996 | |
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| 5,370,685 Endovascular aortic valve replacement | 367 | 1991 | |
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| 4,763,642 Intracavitational brachytherapy | 122 | 1986 | |
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| 5,538,494 Radioactive beam irradiation method and apparatus taking movement of the irradiation area into consideration | 115 | 1995 | |
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| 4,861,520 Capsule for radioactive source | 100 | 1988 | |
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| 4,314,157 Safety lock for radiography exposure device | 33 | 1979 | |
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| 5,605,530 System for safe implantation of radioisotope stents | 89 | 1995 | |
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| 5,897,573 Radioactive medical suture and method of making the same | 31 | 1997 | |
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| 5,120,973 Method and device for inserting a radioactive radiation source into an applicator and withdrawing it therefrom | 48 | 1991 | |
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| 5,803,895 Flexible adaptable plastic elements with equidistantly embedded catheters for radiotherapy | 44 | 1996 | |
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| 5,674,177 Vascular implant | 51 | 1995 | |
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| 5,840,008 Radiation emitting sleeve catheter and methods | 75 | 1995 | |
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| 5,545,132 Helically grooved balloon for dilatation catheter and method of using | 128 | 1993 | |
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| 5,498,227 Retrievable, shielded radiotherapy implant | 138 | 1993 | |
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| 5,084,001 Method and apparatus for effecting radioactive therapy in an animal body | 103 | 1990 | |
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| 5,106,360 Thermotherapeutic apparatus | 413 | 1991 | |
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| 4,936,823 Transendoscopic implant capsule | 158 | 1988 | |
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| 5,417,653 Method for minimizing restenosis | 90 | 1993 | |
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| 4,976,266 Methods of in vivo radiation measurement | 80 | 1988 | |
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| 5,820,553 Identification system and method for radiation therapy | 188 | 1996 | |
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| 5,409,015 Deformable tip super elastic guidewire | 109 | 1993 | |
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| 4,799,479 Method and apparatus for angioplasty | 274 | 1987 | |
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| 4,763,671 Method of treating tumors using selective application of heat and radiation | 122 | 1986 | |
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| 4,963,128 Chest tube and catheter grid for intrathoracic afterload radiotherapy | 41 | 1989 | |
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| 5,030,194 Method and apparatus for effecting radioactive therapy in an animal body | 74 | 1989 | |
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| 4,881,937 Method of treating a part of the body with radioactive material and a trolley for use therein | 60 | 1987 | |
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| 5,843,163 Expandable stent having radioactive treatment means | 71 | 1996 | |
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| 5,213,561 Method and devices for preventing restenosis after angioplasty | 218 | 1992 | |
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| 5,391,139 Real time radiation treatment planning system | 103 | 1994 | |
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| 4,244,357 Method and apparatus for homogeneously irradiating the vaginal mucosa with a linear source uterovaginal applicator | 40 | 1979 | |
| 4,364,376 Method and device for injecting a bolus of material into a body | 39 | 1979 | |
| 4,588,395 Catheter and method | 201 | 1980 | |
| 4,584,991 Medical device for applying therapeutic radiation | 78 | 1983 | |
| 4,897,076 Detachable and remote controllable afterloading device for radiation | 62 | 1985 | |
| 5,199,939 Radioactive catheter | 258 | 1990 | |
| 5,147,282 Irradiation loading apparatus | 85 | 1990 | |
| 5,344,383 Apparatus for radioactive treatment inside the human body and the method using the same | 30 | 1992 | |
| 5,425,720 Medical needle unit | 75 | 1993 | |
| 5,308,356 Passive perfusion angioplasty catheter | 130 | 1993 | |
| 5,653,683 Intracavitary catheter for use in therapeutic radiation procedures | 94 | 1995 | |
| 5,730,698 Balloon expandable temporary radioisotope stent system | 175 | 1995 | |
| 5,816,259 Method for the diagnosis and treatment of cancer by the accumulation of radioactive precipitates in targeted cells | 40 | 1997 | |
| 5,720,717 Intracavitary catheter for use in therapeutic radiation procedures | 105 | 1997 | |
| 5,816,999 Flexible catheter for the delivery of ionizing radiation to the interior of a living body | 52 | 1997 | |