US Patent No: 6,103,295

Number of patents in Portfolio can not be more than 2000

Method of affixing radioisotopes onto the surface of a device

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ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

A method for coating a substrate with a radioisotope comprising is disclosed. The method comprises immersing the substrate within a solution containing a .gamma., .beta..sup.+, .alpha. or .beta..sup.- emitting radioisotope, then exposing the immersed substrate to tuned vibrational cavitation (i.e. ultrasonic) to produce a coated substrate, followed by baking the coated substrate at a temperature below the recrystallization temperature of the substrate. Following this step, the substrate is rinsed and dried. Substrates coated using the method of this invention exhibit very low rates of leaching of the coated radioisotope, and are suitable for use within medical applications.

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First Claim

Related Publications

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MDS NORDION INC.TORONTO4

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chan, Albert Cambridge, MA 31 629
Oelsner, Stephen M Ontario, CA 4 32
Simpson, Thomas J Marshallville, OH 14 60

Cited Art

Patent Info (Count) # Cites Year
 
CORDIS CORPORATION (2)
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5,163,896 Pellet for a radioactive seed 90 1991
 
MEDICAL INNOVATIVE TECHNOLOGIES R&D LIMITED PARTNERSHIP (2)
5,059,166 Intra-arterial stent with the capability to inhibit intimal hyperplasia 402 1989
5,176,617 Use of a stent with the capability to inhibit malignant growth in a vessel such as a biliary duct 218 1991
 
THERAGENICS CORPORATION (2)
4,702,228 X-ray-emitting interstitial implants 132 1985
5,405,309 X-ray emitting interstitial implants 125 1993
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (1)
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ATI MEDICAL, INC. (1)
5,197,940 Local application tumor treatment apparatus 30 1990
 
BRITISH NUCLEAR FUELS PLC (1)
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BRUCE S. HOROWITZ, 494 N.W. 165TH STREET, APT. #C302, MIAMI, FLORIDA 33167 (1)
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INTERVENTIONAL THERAPIES, LLC (1)
5,618,266 Catheter for maneuvering radioactive source wire to site of treatment 136 1994
 
MED INSTITUTE, INC. (1)
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MRKR L.L.C. (1)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (1)
5,707,332 Apparatus and method to reduce restenosis after arterial intervention 108 1995
 
TOYOTA JIDOSHA KABUSHIKI KAISHA (1)
4,818,307 Dispersion strengthened copper-base alloy 15 1987
 
WEINSTEIN, JOSEPH S. (1)
5,213,561 Method and devices for preventing restenosis after angioplasty 218 1992
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (2)
4,900,368 Foamed energy cell 11 1988
5,342,283 Endocurietherapy 197 1990

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
CORDIS CORPORATION (3)
6,800,055 Low attenuating radioactive seeds 18 2001
6,669,621 Method and assembly for containing radioactive materials 13 2001
6,497,646 Intravascular radiotherapy source ribbon having variable radiopacity 39 2001
 
UNIVERSITY OF SOUTH FLORIDA (3)
6,496,717 Radio guided seed localization of imaged lesions 10 1999
8,114,006 Radio guided seed localization of imaged lesions 0 2006
7,881,775 Radio guided seed localization of imaged lesions 0 2009
 
ENDOLOGIX, INC. (2)
6,699,170 Radiation delivery balloon catheter 28 2000
6,685,618 Method for delivering radiation to an intraluminal site in the body 13 2001
 
CORE ONCOLOGY, INC. (1)
6,723,052 Echogenic medical device 29 2001
 
CORNELL RESEARCH FOUNDATION, INC. (1)
7,301,254 High efficiency radio isotope energy converters using both charge and kinetic energy of emitted particles 4 2006
 
ENDOLOGY, INC. (1)
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ETHICON, INC. (1)
7,220,272 Composite staple and method for using same 80 2003
 
KOREA ATOMIC ENERGY RESEARCH INSTITUTE (1)
6,461,666 Radioactive balloon for dilation catheter system and process for preparation thereof 3 2001
 
LOS ALAMOS NATIONAL SECURITY, LLC (1)
6,500,108 Radiation delivery system and method 2 2000
 
MDS INC. (1)
6,676,988 Radioactively coated devices 1 2001
 
MEDI-PHYSICS INC. (1)
7,988,612 Pd brachytherapy seeds 0 2001
 
MEDTRONIC VASCULAR, INC. (1)
7,815,962 Coated stent with evenly distributed therapeutic agent 0 2007
 
RADIANCE MEDICAL SYSTEMS, INC. (1)
6,491,619 Radiation delivery catheters and dosimetry methods 25 2000
 
SCHERING AKTIENGESELLSCHAFT (1)
6,709,693 Stents with a radioactive surface coating, processes for their production and their use for restenosis prophylaxis 2 2000
 
WISCONSIN ALUMNI RESEARCH FOUNDATION (1)
6,479,920 Direct charge radioisotope activation and power generation 52 2001
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (1)
6,680,993 Method of producing Actinium-225 and daughters 2 2000