Antiinflammatory cell adhesion inhibitors
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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-
Aug 29, 2000
Grant Date -
N/A
app pub date -
Oct 10, 1997
filing date -
Oct 10, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to compounds of formula Ix and Ia: ##STR1## wherein (Ix) comprises the regioisomeric form sLe.sup.X and (Ia) comprises the regioisomeric form sLe.sup.A, and R.sup.1 is a lipophilic radical formed from aliphatic or cycloaliphatic units, or a sugar residue which is capped by a .beta.1-O-linked aliphatic or cycloaliphatic unit at the reducing end of the terminal sugar. The compounds of the present invention are useful as inhibitors of increased cell-cell adhesion as well as useful in treating diseases associated with increased cell-cell-adhesion. The compounds of the present invention are also incorporated into pharmaceutical compositions.
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