Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
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United States of America Patent
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Aug 29, 2000
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app pub date -
Jul 27, 1999
filing date -
Jul 28, 1998
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Abstract
Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.
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