Altered polypeptides with increased half-life
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United States of America Patent
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Sep 19, 2000
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app pub date -
Apr 14, 1995
filing date -
Apr 14, 1995
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Abstract
Polypeptides that are cleared from the kidney and do not contain in their original form a Fc region of an IgG are altered so as to comprise a salvage receptor binding epitope of an Fc region of an IgG and thereby have increased circulatory half-life.
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