Phosphate and thiophosphate protecting groups
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United States of America Patent
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-
Sep 19, 2000
Grant Date -
N/A
app pub date -
Mar 16, 1999
filing date -
Mar 16, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel phosphorus protecting groups, intermediates thereof, and synthetic processes for making the same are disclosed. Oligomeric compounds are prepared through the protection of one or more internucleosidic phosphorus functionalities, preferably followed by oxidation and cleavage of the protecting groups to provide oligonucleotides.
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