US Patent No: 6,124,269

Number of patents in Portfolio can not be more than 2000

2-Halo-6-O-substituted ketolide derivatives

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Novel 2-halo-6-O-substituted ketolide derivatives and pharmaceutically acceptable salts and esters thereof having antibacterial activity having a formula ##STR1## compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for their preparation.

Loading the Abstract Image... loading....

First Claim

See full text

all claims..

Related Publications

Loading Related Publications... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
ABBOTT LABORATORIESABBOTT PARK, IL2723

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yan Santa Clara, CA 278 982
Chu, Daniel T Santa Clara, CA 56 689
Clark, Richard F Eden, NY 47 277
Or, Yat Sun Watertown, MA 368 2172
Phan, Ly Tam Quincy, MA 107 314
Platter, Jacob J Berkeley, CA 1 51

Cited Art Landscape

Patent Info (Count) # Cites Year
 
TAISHO PHARMACEUTICAL CO., LTD. (3)
4,990,602 Erythromycin A derivatives 70 1988
5,403,923 6-0-methylerythromycin A derivatives 37 1993
5,631,355 5-O-desosaminylerythronolide a derivatives 30 1994
 
AVENTIS PHARMA S.A. (2)
5,444,051 Erythromycin compounds 63 1993
5,747,467 Erythromycins 34 1996
 
ABBVIE INC. (1)
5,866,549 6-O-substituted ketolides having antibacterial activity 91 1997

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
ENANTA PHARMACEUTICALS, INC. (26)
6,440,942 14-membered macrolides derived from leucomycins 7 2000
6,436,906 9-amino-14-membered macrolides derived from leucomycins 7 2001
6,753,318 6,11-4-carbon bridged erythromycin derivatives 3 2002
6,727,229 11,12-substituted lactone ketolide derivatives having antibacterial activity 0 2002
6,645,941 6,11-3C-bicyclic 9a-azalide derivatives 13 2003
6,878,691 6-11 bicyclic ketolide derivatives 24 2003
7,129,221 6,11-bicyclic erythromycin derivatives 7 2003
6,790,835 Bicyclic macrolide derivatives 0 2003
6,774,115 6-O-substituted bicyclic ketolides 0 2003
6,765,016 Bicyclic ketolide derivatives 0 2003
6,716,820 6-O-substituted bicyclic macrolides 0 2003
6,764,998 6,11-4C-bicyclic 9a-azalide derivatives 14 2003
7,064,110 6-11 bicycle ketolide derivatives 6 2003
7,022,679 Processes for the preparation of 6-11 bicyclic erythromycin derivatives 6 2004
7,910,558 Bridged macrocyclic compounds and processes for the preparation thereof 0 2004
7,049,417 6,11-4-Carbon bridged ketolides 3 2004
7,276,487 9a, 11-3C-bicyclic 9a-azalide derivatives 0 2004
7,414,030 6-11 Bicyclic erythromycin derivatives 4 2005
7,265,094 9N-substituted 6-11 bicyclic erythromycin derivatives 3 2005
7,273,853 6-11 bicyclic ketolide derivatives 14 2005
7,189,704 6-11 bicyclic ketolide derivatives 5 2005
7,135,573 Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine 6 2005
8,273,720 6,11-bicyclolides: bridged biaryl macrolide derivatives 0 2009
8,354,383 6,11-bridged biaryl macrolides 0 2009
8,552,162 Processes for the preparation of 2 fluoro 6-11 bicyclic erythromycin derivatives 0 2009
8,383,785 Anti-bacterial activity of 9-hydroxy derivatives of 6,11-bicyclolides 0 2009
 
KOSAN BIOSCIENCES, INC. (10)
6,451,768 Macrolide antiinfective agents 5 2000
6,395,710 Macrolide antiinfective agents 11 2000
6,514,944 Macrolide antiinfective agents 6 2000
6,593,302 Macrolide antiinfective agents 5 2002
6,794,366 Macrolide antiinfective agents 2 2002
6,939,861 Amido macrolides 1 2003
6,762,168 Macrolide antiinfective agents 4 2003
8,063,021 Ketolide anti-infective compounds 0 2004
RE39836 Macrolide antinfective agents 0 2005
7,595,300 7-quinolyl ketolide antibacterial agents 0 2006
 
ABBVIE INC. (3)
6,455,680 Methods utilizing aryl thioimines in synthesis of erythromycin derivatives 2 2000
7,071,314 Arylation method for the functionalization of O-allyl erythromycin derivatives 0 2002
6,998,390 Oxolide antibacterials 1 2003
 
ORTHO-MCNEIL PHARMACEUTICAL, INC. (3)
6,458,771 Ketolide antibacterials 6 2000
6,399,582 Ketolide antibacterials 32 2000
6,590,083 Ketolide antibacterials 7 2000
 
AVENTIS PHARMA S.A. (2)
6,352,983 2-halogenated derivatives of 5-0 desosaminyl-erythronolide A, their preparation process and their antibiotic use 1 1999
RE39743 2-halogenated derivatives of 5-0 desosaminyl-erythronolide a, their preparation process and their antibiotic use 0 2002
 
CLEMSON UNIVERSITY (2)
7,071,288 Terpolymers from lactide 2 2004
7,754,826 Copolymers from lactide 0 2006
 
CHIRON CORPORATION (1)
7,163,924 Ketolide derivatives 1 2004
 
Enanra Pharmaceuticals, Inc. (1)
6,841,664 6,11-4-carbon bridged ketolides 2 2002
 
Enanta Pharmaceuticals (1)
6,720,308 Anhydrolide derivatives having antibacterial activity 2 2002
 
PFIZER PRODUCTS INC. (1)
6,809,080 Macrolide antibiotics 0 2001
 
PLIVA D.D. (1)
6,900,183 Macrolide antibiotics 1 2001

Full Text

 
loading....