CYP2D fluorescent assay reagents
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Oct 10, 2000
Grant Date -
N/A
app pub date -
Jul 12, 1999
filing date -
Jul 16, 1998
priority date (Note) -
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Abstract
Novel fluorescent substrates of the human P450 enzyme CYP2D6 are provided. Also provided are methods for their manufacture and use. These substrates are useful in assessing CYP2D6 enzyme activity and in selecting compounds which inhibit CYP2D6 enzyme activity and, in particular, for identifying potential adverse drug interactions which are mediated by inhibition of CYP2D6 enzyme activity.
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