Covalent attachment of unmodified nucleic acids to silanized solid phase surfaces
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United States of America Patent
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Oct 24, 2000
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N/A
app pub date -
Jun 23, 1998
filing date -
Jun 6, 1997
priority date (Note) -
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Abstract
This invention relates to a composition having a nucleic acid molecule covalently coupled to a solid support by means of a covalent linkage. The nucleic acid molecule is covalently coupled to the solid support by a silane. The composition can be used in nucleic acid hybridization assays and sequencing by hybridization assays.
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