Targeted contrast agents for diagnostic and therapeutic use
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United States of America Patent
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Oct 31, 2000
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app pub date -
Sep 17, 1997
filing date -
Jun 7, 1995
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Abstract
Novel contrast agents which may be used for diagnostic and therapeutic use. The compositions may comprise a lipid, a protein, polymer and/or surfactant, and a gas, in combination with a targeting ligand. In preferred embodiments, the targeting ligand targets coagula, including emboli and/or thrombi, particularly in patients suffering from an arrhythmic disorder. The contrast media can be used in conjunction with diagnostic imaging, such as ultrasound, as well as therapeutic applications, such as therapeutic ultrasound.
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