Multiplex genotyping using fluorescent hybridization probes
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United States of America Patent
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Oct 31, 2000
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N/A
app pub date -
Sep 30, 1998
filing date -
Sep 30, 1998
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Abstract
The present invention is directed to a mutation detection kit and method of analyzing multiple loci of one or more nucleic acid sequences for the presence of mutations or polymorphisms. More particularly, the present invention relates to the use of the polymerase chain reaction (PCR) and fluorescently labeled oligonucleotide hybridization probes to identify mutations and polymorphisms based on melting curve analysis of the hybridization probes.
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