Proteins with mutations to decrease N-terminal methylation

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United States of America Patent

PATENT NO 6140071
SERIAL NO

08188374

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Abstract

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This invention relates to proteins with N-terminal modifications in their amino acid sequence that reduce or eliminate the methylation of the N-terminal methionine that occurs when such proteins are produced in bacteria such as E. coli.

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Patent Owner(s)

Patent OwnerAddress
BAXTER BIOTECH TECHNOLOGY SARLROUTE DE PIERRE-A-BOT 111 CH 2000 NEUCHATEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aitken, Jacqueline F Louisville, CO 5 14
Apostol, Izydor Z Boulder, CO 4 121
Levine, Joseph D Louisville, CO 3 1
Lippincott, Julie A Boulder, CO 2 0

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