Type S.sub.3 N.sub.2 chelators for radioactive isotopes, their metal complexes and their diagnostic and therapeutical use
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United States of America Patent
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Nov 7, 2000
Grant Date -
N/A
app pub date -
Mar 8, 1996
filing date -
Mar 31, 1993
priority date (Note) -
Expired
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Abstract
This invention relates to new bifunctional chelating agents with intermittent chalcogen atoms, pharmaceuticals containing these compounds, their use in radiodiagnostics and radiotherapy, and methods for the production of these compounds. The compound according to the invention has the general formula (I) M--L wherein M represents a radionuclide of Tc or Re and L a ligand of the general formula (II) B--CO--CR.sup.1 R.sup.2 --A--CR.sup.3 R.sup.4 --CO--D (II) These new, bifunctional chelating agents with intermittent chalcogen atoms and their coupling products with compounds that accumulate specifically are suited for producing radiopharmaceuticals for diagnostic and therapeutic purposes.
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