Parallel fixed bed reactor and fluid contacting apparatus
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United States of America Patent
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Nov 21, 2000
Grant Date -
N/A
app pub date -
Jun 9, 1998
filing date -
Jun 9, 1998
priority date (Note) -
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Abstract
The present invention discloses an apparatus and method for rapid analysis of members of a combinatorial library. The apparatus includes a plurality of vessels for containing individual library members and a fluid handling system that apportions a test fluid about equally between each of the vessels. This allows for simultaneous screening of library members by detecting changes in test fluid following contact with individual library members. Fluid flow through each of the vessels is controlled using passive flow restrictors or active flow controllers to ensure that each library member contacts approximately the same amount of test fluid per unit time. The disclosed apparatus is especially useful for screening library members based on their ability to catalyze the conversion of fluid reactants.
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