Reagents with enhanced performance in clinical diagnostic systems

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United States of America Patent

PATENT NO 6150128
SERIAL NO

08853511

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Abstract

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It has been found that imidazole and related buffers enhance the activity of certain preservatives, for example either (1) a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one or (2) 5-bromo-5-nitro-1,3-dioxane, that are used in clinical diagnostic reagents. It has also been found that these buffers and certain surfactants, such as Brij 700 and related hydrophilic surfactants, enhance the precision and accuracy of enzyme biosensors.

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Patent Owner(s)

Patent OwnerAddress
SIEMENS HEALTHCARE DIAGNOSTICS INC511 BENEDICT AVE TARRYTOWN NY 10591

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Uretsky, Laura S Milford, MA 7 727

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