Polyketide synthase enzymes and recombinant DNA constructs therefor
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United States of America Patent
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Nov 21, 2000
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app pub date -
Sep 16, 1998
filing date -
Sep 16, 1998
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Abstract
Host cells comprising recombinant vectors encoding the FK-520 polyketide synthase and FK-520 modification enzymes can be used to produce the neuroimmunophilin FK-520 polyketide. Recombinant DNA constructs comprising one or more FK-520 polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variety of different polyketides with application in agriculture, medicine, and animal health.
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