Importance

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Abstract

The present invention provides a method for producing a calcium phosphate coating film on the surface of a substrate, even a substrate which has poor heat resistance. The method comprises the steps of soaking a substrate in a first solution containing phosphate ions, inter alia, aqueous solutions of a basic phosphate salt such as Na.sub.3 PO.sub.4 or Na.sub.2 HPO.sub.4 ; removing the substrate and drying it; and soaking the substrate in a second solution (aqueous solution) containing calcium ions, to thereby obtain a coating film comprising hydroxyapatite or a mixture containing hydroxyapatite and a hydroxyapatite precursor. The substrate removed from the second solution may be soaked in a third solution (aqueous solution) containing an apatite component at a substantially saturated or supersaturated concentration, to thereby form a hydroxyapatite coating film. There may be used substrates formed of metals, ceramics, organic polymer materials, etc. The method is applicable to a substrate having poor heat resistance, such as synthetic resin fabric, due to omission of high-temperature treatment.

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First Claim