Phenylpyridyl compounds for inhibiting phosphodiesterase IV and methods of using same
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United States of America Patent
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Nov 28, 2000
Issued Date -
N/A
app pub date -
Nov 13, 1997
filing date -
Jan 10, 1995
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Abstract
Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram as well as with improved selectivity with regard to PDE III inhibition. In certain aspects of the invention, the compounds also demonstrate PDE V inhibition. Pharmaceutical compositions containing the same and methods of treatment are also disclosed.
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