Cellular apoptosis susceptibility protein (CSP) and antisense CSP

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United States of America Patent

PATENT NO 6156564
SERIAL NO

08973626

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Abstract

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The cDNA and amino acid sequences for a cellular apoptosis susceptibility (CAS) protein are used to detect expression and amplification of CAS gene in normal and cancer cells. An antisense CAS gene sequence introduced into living cells inhibits CAS protein activity and thus prevents or inhibits apoptosis in the cells.

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Patent Owner(s)

Patent OwnerAddress
HEALTH AND HUMAN SERVICES UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY DEPARTMENT OFNATIONAL INSTITUTES OF HEALTH 6011 EXECUTIVE BLVD STE 325 ROCKVILLE MD 20852

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brinkmann, Ulrich Kensington, MD 116 1819
Pastan, Ira Potomac, MD 66 1404

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