XIAP IRES and uses thereof
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United States of America Patent
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Dec 12, 2000
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N/A
app pub date -
Jul 24, 1998
filing date -
Jul 24, 1998
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Abstract
The invention features purified nucleic acid encoding a novel internal ribosome entry site (IRES) sequence from the X-linked inhibitor of apoptosis (XIAP) gene. The invention also features methods for using the XIAP IRES to increase cap-independent translation of polypeptide coding sequences linked to the XIAP IRES, and methods for isolating compounds that modulate cap-independent translation.
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