Vascular graft impregnated with a heparin-containing collagen sealant
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United States of America Patent
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Dec 19, 2000
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app pub date -
Dec 21, 1998
filing date -
Aug 12, 1994
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Abstract
A heparin-collagen dispersion is provided for impregnating a vascular prosthesis with heparin and collagen. The dispersion is prepared at an alkaline pH to allow the addition of heparin without causing the agglutination of collagen from the dispersion. The impregnation of collagen and heparin within the prosthesis effectively prevents blood loss and thrombus formation after implantation of the prosthesis.
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