Sustained release compositions and a method of preparing pharmaceutical compositions

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6162467
SERIAL NO

09370270

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form agglomerates, breaking the agglomerates to give controlled release particles and optionally continuing the mechanical working with the optional addition of a low percentage of the carrier or diluent.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
EURO-CELTIQUE S.A.LUXEMBOURG94

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Challis, Deborah Kent, GB 5 767
Heafield, Joanne Cambridge, GB 11 1221
Knott, Trevor John Essex, GB 11 1105
Leslie, Stewart Thomas Cambridge, GB 21 1972
Malkowska, Sandra Therese Antoinette Cambridge, GB 16 1688
Miller, Ronald Brown Basel, CH 18 1861
Prater, Derek Allan Cambridge, GB 31 2043

Cited Art Landscape

Patent Info (Count) # Cites Year
 
SCHWARZ PHARMA AG (2)
* 5453283 Orally administered solvent-free pharmaceutical preparation with delayed active-substance release, and a method of preparing the preparation 22 1993
* 5472710 Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture 54 1994
 
ALFA WASSERMANN S.P.A. (1)
* 5300300 Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts 30 1992
 
NOVARTIS AG (1)
* 5403593 Melt granulated compositions for preparing sustained release dosage forms 67 1992
 
Merrell Dow Pharmaceuticals Inc. (1)
* 4421736 Sustained release diethylpropion compositions 85 1982
 
NIRO HOLDING A/S (1)
* 5030400 Process and an apparatus for agglomeration of a powdery material 91 1990
 
EURO-CELTIQUE S.A. (5)
* 4844907 Pharmaceutical composition comprising analgesic and anti-inflammatory agent 160 1986
* 5500227 Immediate release tablet cores of insoluble drugs having sustained-release coating 235 1993
* 5849240 Method of preparing sustained release pharmaceutical compositions 221 1996
* 5843480 Controlled release diamorphine formulation 148 1996
* 5965163 Substained release compositions and a method of preparing pharmaceutical compositions 195 1997
 
SCHERING CORPORATION (1)
* 5162117 Controlled release flutamide composition 84 1991
 
PURDUE PHARMA L.P. (9)
* 4828836 Controlled release pharmaceutical composition 235 1987
* 4834985 Controlled release pharmaceutical composition 248 1987
* 4990341 Controlled release hydromorphone composition 209 1989
* 5266331 Controlled release oxycodone compositions 301 1991
* 5273760 Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer 302 1991
* 5286493 Stabilized controlled release formulations having acrylic polymer coating 298 1992
* 5549912 Controlled release oxycodone compositions 292 1993
* 5580578 Controlled release formulations coated with aqueous dispersions of acrylic polymers 276 1993
* 5639476 Controlled release formulations coated with aqueous dispersions of acrylic polymers 601 1995
 
TEIJIN LIMITED (1)
* 4801458 Sustained release pharmaceutical plaster 98 1987
 
EUROCELTIQUE S.A., 122, BOULEVARD DE LA PETRUSSE, LUXEMBOURG (1)
* 4844909 Controlled release hydromorphone composition 203 1987
 
TAKEDA PHARMACEUTICAL COMPANY LIMITED (1)
* 5026560 Spherical granules having core and their production 183 1988
 
Indresco Inc. (1)
4329794 Ripping attachment for dragline 38 1980
 
ALPHARMA PHARMACEUTICALS, LLC (2)
* 5202128 Sustained release pharmaceutical composition 217 1990
* 5330766 Sustained release pharmaceutical composition 184 1993
 
HOECHST AKTIENGESELLSCHAFT (1)
* 4935246 Process for the coating of granules 131 1988
 
Ethical Pharmaceuticals Limited (1)
* 4880830 Slow release formulation 54 1987
 
ELAN PHARMA INTERNATIONAL LIMITED (1)
* 4917899 Controlled absorption diltiazem formulation 56 1987
 
DRUGTECH CORPORATION (1)
* 5133974 Extended release pharmaceutical formulations 332 1990
 
Sansho Co., Ltd. (1)
* 5204119 External preparation comprising calcium silicate 35 1991
 
DepoMed Systems, Inc. (1)
* 5007790 Sustained-release oral drug dosage form 192 1989
 
AKZO N.V. (1)
* 4613619 Anti-arrhythmic amino-alcohols 20 1985
 
THE ROCKEFELLER UNIVERSITY (1)
* 4987136 Method for controlling gastrointestinal dysmotility 147 1986
 
GLATT GMBH (2)
* 4967486 Microwave assisted fluidized bed processor 33 1989
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GACELL LABORATORIES AB (1)
* 5178868 Dosage form 82 1991
 
PHARMASCIENCES, INC. (1)
* 4925675 Erythromycin microencapsulated granules 29 1988
 
WARNER-LAMBERT COMPANY LLC (2)
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CADBURY ADAMS USA LLC (1)
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NAPP PHARMACEUTICAL GROUP LIMITED (1)
* 5591452 Controlled release formulation 119 1994
 
Ortho Pharmaceutical Corporation (1)
* 5395626 Multilayered controlled release pharmaceutical dosage form 125 1994
 
FOREST LABORATORIES, INC. (1)
* 4389393 Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose 336 1982
 
PURDUE PHARMA COMPANY, THE (2)
* 4861598 Controlled release bases for pharmaceuticals 274 1986
* 4970075 Controlled release bases for pharmaceuticals 235 1989
 
YAMANOUCHI PHARMACEUTICAL CO., LTD. (2)
* 4343789 Sustained release pharmaceutical composition of solid medical material 103 1980
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REVLON CONSUMER PRODUCTS CORPORATION (1)
* 5271934 Encapsulated antiperspirant salts and deodorant/antiperspirants 78 1992
 
SANKYO COMPANY, LIMITED (1)
* 4533562 Method of preparing coated solid preparations 52 1984
 
SPRING AG METALLWARENFABRIKEN AG (1)
* 5292461 Process for the production of pellets 84 1991
 
F.H. FAULDING & CO. LIMITED (1)
* 5196203 Theophylline dosage form 69 1991
 
PUREUE PHARMA L.P. (1)
* 4834984 Controlled release dihydrocodeine composition 191 1987
 
TAKEDA CHEMICAL INDUSTRIES, LTD. (1)
* 5443846 Granulated preparations and method of producing the same 23 1994
 
DUQUESNE UNIVERSITY OF THE HOLY GHOST, A CORP. OF PA. (1)
* 5169645 Directly compressible granules having improved flow properties 191 1989
 
BASF AKTIENGESELLSCHAFT (2)
* 4801460 Preparation of solid pharmaceutical forms 135 1987
* 5073379 Continuous preparation of solid pharmaceutical forms 101 1989
 
TCF NATIONAL BANK (1)
* 5126145 Controlled release tablet containing water soluble medicament 139 1990
 
Shionogi & Co., Ltd. (1)
* 5023089 Sustained-release preparations and the process thereof 73 1989
 
PHARMACIA AB (1)
* 5807583 Process for the preparation of sustained release pellets 17 1995
 
MITSUI CHEMICALS, INC. (1)
* 4621114 Propylene resin composition 34 1984
* Cited By Examiner

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (3)
8410129 Treatment for paresis/paralysis 2 2003
* 2003/0166,670 Use of an opioid compound to treat a neurologic or neurogenic disorder 6 2003
* 2004/0224,949 Modified release formulations of at least one form of tramadol 2 2003
 
ATHPHARMA (1)
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VALEANT INTERNATIONAL BERMUDA (2)
8128957 Modified release compositions of at least one form of tramadol 0 2004
8158147 Modified release formulations of at least one form of tramadol 0 2007
 
AMOREPACIFIC CORPORATION (1)
* 2006/0153,915 Sustained-release preparations and method for producing the same 31 2004
 
BIOVAIL LABORATORIES INTERNATIONAL SRL (1)
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EURO-CELTIQUE S.A. (2)
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PALADIN LABS INC. (2)
8487002 Controlled-release compositions 0 2005
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PURDUE PHARMA L.P. (106)
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7943173 Pharmaceutical combinations of oxycodone and naloxone 13 2002
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7842311 Tamper-resistant oral opioid agonist formulations 23 2003
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7842309 Tamper-resistant oral opioid agonist formulations 19 2003
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7682632 Tamper-resistant oral opioid agonist formulations 29 2003
7658939 Tamper-resistant oral opioid agonist formulations 98 2003
9149436 Pharmaceutical product comprising a sequestered agent 0 2004
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8518925 Opioids for the treatment of the chronic obstructive pulmonary disease (COPD) 6 2005
8465774 Sequestered antagonist formulations 9 2006
7419686 Opioid agonist/antagonist combinations 70 2006
7749542 Opioid agonist/antagonist combinations 45 2008
9271940 Immediate release pharmaceutical compositions comprising oxycodone and naloxone 0 2010
8105631 Opioid agonist/antagonist combinations 44 2010
8236351 Tamper-resistant oral opioid agonist formulations 9 2010
8980291 Controlled release hydrocodone formulations 6 2010
8231901 Opioid agonist formulations with releasable and sequestered antagonist 6 2011
8808740 Encased tamper resistant controlled release dosage forms 16 2011
9233073 Tamper resistant solid oral dosage forms 3 2011
8673355 Opioid agonist/antagonist combinations 14 2011
8846090 Matrix for sustained, invariant and independent release of active compounds 16 2012
8518443 Opioid agonist formulations with releasable and sequestered antagonist 9 2012
8357399 Tamper-resistant oral opioid agonist formulations 7 2012
8586088 Tamper-resistant oral opioid agonist formulations 5 2012
* 9060976 Pharmaceutical formulation containing gelling agent 26 2012
9040084 Pharmaceutical formulation containing gelling agent 14 2013
9005659 Pharmaceutical formulation containing gelling agent 0 2013
9308170 Pharmaceutical formulation containing gelling agent 2 2013
8758825 Sequestered antagonist formulations 0 2013
* 8609683 Pharmaceutical formulation containing gelling agent 38 2013
* 8529948 Pharmaceutical formulation containing gelling agent 31 2013
8999961 Pharmaceutical formulation containing gelling agent 14 2013
8815287 Opiod agonist formulations with releasable and sequestered antagonist 0 2013
9744136 Encased tamper resistant controlled release dosage forms 0 2013
9393206 Encased tamper resistant controlled release dosage forms 0 2013
8936812 Tamper-resistant oral opioid agonist formulations 1 2013
8846091 Matrix for sustained, invariant and independent release of active compounds 15 2013
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9084729 Abuse-resistant controlled-release opioid dosage form 3 2013
8975271 Controlled release hydrocodone formulations 0 2013
8969369 Abuse-resistant controlled-release opioid dosage form 15 2013
9149533 Tamper resistant pharmaceutical formulations 4 2014
9056051 Abuse-resistant controlled-release opioid dosage form 5 2014
9616030 Tamper resistant pharmaceutical formulations 0 2014
9205082 Opioid agonist/antagonist combinations 1 2014
9060940 Controlled release hydrocodone 12 2014
9555000 Pharmaceutical preparation containing oxycodone and naloxone 1 2014
9044435 Pharmaceutical formulation containing gelling agent 26 2014
8975273 Controlled release hydrocodone formulations 1 2014
9655855 Matrix for sustained, invariant and independent release of active compounds 1 2014
8932630 Opioid agonist/antagonist combinations 4 2014
8951555 Controlled release hydrocodone formulations 15 2014
9456989 Tamper-resistant oral opioid agonist formulations 0 2014
9023401 Controlled release hydrocodone formulations 16 2014
9308171 Pharmaceutical formulation containing gelling agent 2 2015
9056052 Controlled release hydrocodone formulations 15 2015
9662326 Systems for treating an opioid-induced adverse pharmacodynamic response 0 2015
9056107 Controlled release hydrocodone formulations 3 2015
9387173 Pharmaceutical formulation containing gelling agent 3 2015
9278073 Tamper-resistant oral opioid agonist formulations 1 2015
9662399 Tamper resistant pharmaceutical formulations 0 2015
9655971 Tamper resistant pharmaceutical formulations 0 2015
9579389 Methods of preparing tamper resistant pharmaceutical formulations 0 2015
9545448 Tamper resistant pharmaceutical formulations 0 2015
9320717 Controlled release hydrocodone formulations 2 2015
9278074 Controlled release hydrocodone formulations 2 2015
9289391 Controlled release hydrocodone formulations 10 2015
9168252 Abuse-resistant controlled-release opioid dosage form 2 2015
9161937 Abuse-resistant controlled-release opioid dosage form 3 2015
9517206 Pharmaceutical formulation containing gelling agent 0 2015
9205055 Controlled release hydrocodone formulations 10 2015
9205056 Controlled release hydrocodone formulations 10 2015
9198863 Controlled release hydrocodone formulations 10 2015
9522115 Pharmaceutical formulation containing gelling agent 0 2015
9498456 Pharmaceutical formulation containing gelling agent 0 2015
9517207 Pharmaceutical formulation containing gelling agent 1 2015
9387174 Pharmaceutical formulation containing gelling agent 3 2015
9283216 Abuse-resistant controlled-release opioid dosage form 1 2015
9283221 Abuse-resistant controlled-release opioid dosage form 1 2015
9707180 Methods of preparing tamper resistant solid oral dosage forms 0 2016
9820983 Immediate release pharmaceutical compositions comprising oxycodone and naloxone 0 2016
9358230 Abuse-resistant controlled-release opioid dosage form 1 2016
9345701 Abuse-resistant controlled-release opioid dosage form 1 2016
9693961 Pharmaceutical formulation containing gelling agent 1 2016
9572804 Controlled release hydrocodone formulations 0 2016
9572805 Controlled release hydrocodone formulations 0 2016
9526724 Controlled release hydrocodone formulations 2 2016
9517236 Controlled release hydrocodone formulations 2 2016
9504681 Controlled release hydrocodone formulations 2 2016
9750703 Encased tamper resistant controlled release dosage forms 0 2016
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9522118 Encased tamper resistant controlled release dosage forms 0 2016
9669022 Controlled release hydrocodone formulations 0 2016
9511066 Abuse-resistant controlled-release opioid dosage form 1 2016
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9801828 Tamper resistant oral opioid agonist formulations 0 2016
9757341 Pharmaceutical formulation containing gelling agent 0 2016
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9669023 Controlled release hydrocodone formulations 0 2016
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7399488 Abuse-deterrent pharmaceutical compositions of opiods and other drugs 115 2003
* 2004/0052,731 Abuse-deterrent pharmaceutical compositions of opiods and other drugs 55 2003
7771707 Abuse-deterrent drug formulations 27 2005
* 2005/0281,748 Abuse-deterrent drug formulations 28 2005
* 2008/0260,819 SUSTAINED RELEASE COMPOSITIONS OF DRUGS 29 2008
* 2008/0199,530 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITIONS OF OPIOIDS AND OTHER DRUGS 14 2008
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8449909 Abuse-deterrent drug formulations 21 2010
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9044398 Abuse-deterrent pharmaceutical compositions of opiods and other drugs 5 2012
8758813 Abuse-deterrent drug formulations 5 2013
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9763883 Abuse-deterrent drug formulations 0 2014
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ATHPHARMA LIMITED (1)
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PFIZER INC. (1)
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8445018 Abuse resistant drug formulation 24 2008
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LABOPHARM EUROPE LIMITED - PARTIAL INTEREST (ENTIRE INTEREST OWNED BY LABOPHARM INC., LABOPHARM EUROPE LIMITED, AND LABOPHARM (BARBADOS) LIMITED) (5)
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8414919 Sustained drug release composition 5 2010
 
ALPHARMA PHARMACEUTICALS, LLC (7)
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8623418 Pharmaceutical composition 1 2008
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8846104 Pharmaceutical compositions for the deterrence and/or prevention of abuse 0 2012
 
The P.F. Laboratories, Inc. (5)
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8182836 Abuse-resistant oral dosage forms and method of use thereof 11 2009
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* Cited By Examiner