Isolation, characterization, and use of the human .beta. subunit of the high affinity receptor for immunoglobulin E
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United States of America Patent
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Jan 9, 2001
Grant Date -
N/A
app pub date -
Jun 23, 1998
filing date -
Apr 16, 1992
priority date (Note) -
Expired
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Abstract
The present invention relates to nucleic acid sequences, encoding amino acid sequences of the .alpha., .beta., and .gamma. subunits of the high affinity receptor for immunoglobulin E, and for amino acid sequences of the subunits. The invention further relates to a method of producing the receptor by expressing cDNA for its .alpha., .beta., and .gamma. subunits in a host cell simultaneously. Aspects of the invention are methods and compositions to inhibit the function of the human beta subunit, thereby treating or preventing allergic reactions.
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