US Patent No: 6,175,420

Number of patents in Portfolio can not be more than 2000

Optical sensors for cell processing systems

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ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

An optical sensor is disclosed for use in an interactive cell processing system that includes a plurality of sensors arranged for monitoring and providing sensor data to a control module that directs processing of biological cells. The sensors including an optical sensor for characterizing a fluid transferred in a sterile manner during the processing. The optical sensor includes a light source, a light detector, a cuvette and a control circuit. The light source is connected to a control circuit and is constructed and arranged to emit light of at least one selected wavelength directed toward the fluid. The cuvette is constructed as a part of a fluid distribution manifold that includes several conduits for transferring the sterile fluid during the processing, wherein the cuvette is constructed and arranged to convey the fluid. The light detector is connected to the control circuit and is constructed and arranged to detect light that was emitted from the source and has interacted with the fluid flowing inside the cuvette. The control circuit is constructed and arranged to characterize the fluid in the cuvette based on the detected light.

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First Claim

Related Publications

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Patent Owner(s)

Patent OwnerAddressTotal Patents
VELICO MEDICAL, INC.BEVERLY, MA33

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barry, Donald Norwood, MA 21 214
Edwards, Bruce H White Bear Lake, MN 26 244
Fennelly, Jeremy Watertown, MA 2 30
Jorgensen, Glen Marlboro, MA 25 135

Cited Art

Patent Info (Count) # Cites Year
 
FRESENIUS AG (2)
5,318,512 Blood separation device 49 1992
5,386,734 Centrifuge system for the separation of blood into its components 46 1993
 
ARTEL, INC. (1)
5,064,282 Photometric apparatus and method for measuring hemoglobin 20 1989
 
BAXTER INTERNATIONAL INC. (1)
4,227,814 Optical density detector 47 1979
 
COBE CARDIOVASCULAR, INC. (1)
5,505,685 Automation of plasma sequestration 55 1995
 
GAMBRO BCT, INC. (1)
4,810,090 Method and apparatus for monitoring blood components 50 1987
 
HEMOCUE AB (1)
D337388 Cuvette for an optical analysis of liquids 6 1991
 
LIFESTREAM INTERNATIONAL, INC. (1)
5,385,539 Apparatus for monitoring hematocrit levels of blood 36 1992
 
SAFETY SYRINGES, INC. (1)
5,356,392 Shielded blood collection tube holder 77 1994
 
TERUMO BCT, INC. (1)
5,734,464 Red blood cell spillover detection technique 11 1996
 
THE CBR INSTITUTE FOR BIOMEDICAL RESEARCH, INC. (1)
5,612,207 Method and apparatus for encapsulation of biologically-active substances in cells 26 1995
 
UNION ESPANOLA DE EXPLOSIVOS, S.A. (1)
5,449,622 Method and apparatus for analyzing stained particles 42 1994

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
VELICO MEDICAL, INC. (7)
6,852,074 Biological processing apparatus for expressing fluid material 13 1998
7,011,742 Blood product transfer system 12 2002
7,651,457 Expandable processing and expression chamber 1 2003
7,425,192 Apparatus for method for expressing fluid materials 2 2004
7,645,377 Blood product transfer system 0 2006
7,594,663 Rotating seals for cell processing systems 0 2006
8,133,165 Expandable processing and expression chamber 0 2010
 
BATTELLE MEMORIAL INSTITUTE (4)
7,397,601 Optical system for cell imaging 2 2005
7,560,277 Method and apparatus for detection of rare cells 1 2006
7,495,827 Sample tube handling apparatus 1 2006
7,978,405 Optical system for cell imaging 0 2008
 
BAXTER INTERNATIONAL INC. (4)
6,884,228 Automated system adaptable for use with different fluid circuits 4 2001
6,808,503 Automated system and method for pre-surgical blood donation and fluid replacement 1 2001
6,706,008 Automated system and method for withdrawing compounds from blood 27 2001
6,582,386 Multi-purpose, automated blood and fluid processing systems and methods 11 2001
 
CYTOMED, INC. (2)
7,060,018 Centrifuge apparatus for processing blood 3 2003
7,407,472 Centrifuge apparatus for processing blood 2 2005
 
FINESSE SOLUTIONS, INC. (1)
7,369,226 Optical sensor device having variable optical path length 1 2004
 
MEDICAL VISION AB (1)
7,981,073 Method and device for irrigation of body cavities 1 2007
 
SORIN GROUP ITALIA S.R.L. (1)
7,311,849 Control device for the separate collection of blood components in output from a blood centrifugation cell 2 2004